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教授

何祖平

2023年02月08日 20:09  點擊:[]

名字:何祖平

照片:

職稱:二級教授

職務(wù):bwin必贏院長

研究生招生專業(yè):基礎(chǔ)醫(yī)學(xué)(博士學(xué)位);病理學(xué)與病理生理學(xué)(碩士學(xué)位)

聯(lián)系電話:0731-88912446(Office)

電子郵箱:zupinghe@hunnu.edu.cn

簡介:

何祖平教授,湖南師范大學(xué)醫(yī)學(xué)部黨工委委員(正處級)、基礎(chǔ)bwin必贏院長。曾任bwin必贏院長,上海市男科學(xué)研究所所長。二級教授,“瀟湘學(xué)者”特聘教授,博士生導(dǎo)師。上海高校特聘教授(東方學(xué)者)、湖湘高層次人才聚焦工程-杰出創(chuàng)新人才?!澳J絼游锱c干細胞生物學(xué)”湖南省重點實驗室主任、“生殖與轉(zhuǎn)化醫(yī)學(xué)”湖南省工程研究中心主任。主持國家自然科學(xué)基金重點項目、國家重點研發(fā)計劃課題、國家重大科學(xué)研究課題(2項)、國家自然科學(xué)基金面上項目(5項)、湖南省重大專項課題、湖南省重點研發(fā)計劃項目、上海市科委重點項目、湖南省教育廳重點項目。“臨床醫(yī)學(xué)”國家一流專業(yè)建設(shè)點負責人,“基礎(chǔ)醫(yī)學(xué)”湖南省“十四五”重點學(xué)科建設(shè)負責人,“湖南省工人先鋒號”創(chuàng)新團隊帶頭人。國家杰出青年基金評審專家,長江學(xué)者(特聘教授、講座教授、青年學(xué)者)評審專家,科技創(chuàng)新領(lǐng)軍人才評審專家。國家重點研發(fā)計劃項目、國家自然科學(xué)基金基礎(chǔ)科學(xué)中心項目、重大項目、重點項目、國際合作重點項目、面上項目、青年項目的通訊評審專家和/或會議評審專家。國家優(yōu)秀青年基金(國內(nèi)、海外)評審專家。湖南省“百人計劃”會評專家。上海市自然科學(xué)獎主審專家(通訊評審、會議評審)。

長期從事生殖醫(yī)學(xué)、細胞生物學(xué)與分子生物學(xué)研究。其研究成果已發(fā)表或接受發(fā)表在國際著名期刊,如Cell Death and Differentiation(IF:15.828)、Research(IF:11.0,2篇研究論文)、Molecular Therapy-Nucleic Acids(IF:10.18,6篇研究論文)、Cell Death and Disease(IF:9.685)、Cellular and Molecular Life Sciences(IF:9.26,3篇研究論文)、Stem Cell Reports(IF:7.765,2篇研究論文)、Stem Cells(IF:7.74,3篇研究論文)等。他以通訊作者或第一作者已發(fā)表發(fā)表SCI收錄論文91篇,合計SCI影響因子(IF)>450;IF>5的論文43篇,IF>10研究論文9篇。論文被Nature Genetics、Cell Stem Cell等SCI引用3700多次。單篇論文最高SCI引用370多次。擔任SCI期刊Frontiers in Cell and Developmental Biology副主編、Asian Journal of Andrology編委。獲得湖南省自然科學(xué)獎二等獎(排名第一)、教育部科技進步獎二等獎、上海市醫(yī)學(xué)科技獎一等獎。

工作經(jīng)歷:

2024年8月24日-至今 湖南師范大學(xué),醫(yī)學(xué)部黨工委委員,基礎(chǔ)bwin必贏院長

二級教授,“瀟湘學(xué)者”特聘教授,博士生導(dǎo)師

2017年10月-2024年8月 湖南師范大學(xué),bwin必贏院長,二級教授

“瀟湘學(xué)者”特聘教授,博士生導(dǎo)師

2011年2月-2017年10月 上海交通大學(xué)bwin必贏,研究員,“東方學(xué)者”特聘教授

博士生導(dǎo)師

2008年3月-2011年2月美國喬治城大學(xué),助理教授

2004年2月-2008年2月美國喬治城大學(xué),博士后

社會(學(xué)術(shù))兼職

1.“模式動物與干細胞生物學(xué)”湖南省重點實驗室主任

2.“生殖與轉(zhuǎn)化醫(yī)學(xué)”湖南省工程研究中心主任

3.上海市生殖醫(yī)學(xué)重點實驗室學(xué)術(shù)委員會委員

4.“危重醫(yī)學(xué)代謝組學(xué)”湖南省重點實驗室學(xué)術(shù)委員會副主任委員

5.“動物腸道功能調(diào)控”湖南省重點實驗室學(xué)術(shù)委員會副主任委員

6.“湖南省動物腸道生態(tài)與健康”國際創(chuàng)新合作基地學(xué)術(shù)委員會副主任委員

7.“模式動物與干細胞生物學(xué)”湖南省重點實驗室學(xué)術(shù)委員會委員

8.“生殖與轉(zhuǎn)化醫(yī)學(xué)”湖南省工程研究中心專家技術(shù)委員會委員

9.“小分子靶向藥物研究與創(chuàng)制”湖南省重點實驗室學(xué)術(shù)委員會委員

10.“分子流行病學(xué)”湖南省重點實驗室學(xué)術(shù)委員會委員

11.避孕節(jié)育(生殖健康)新技術(shù)國家地方聯(lián)合工程實驗室學(xué)術(shù)委員會委員

12.中國生理學(xué)學(xué)會生殖科學(xué)專業(yè)委員會委員

13.中國動物學(xué)會生殖生物學(xué)分會理事

14.國際生殖研究學(xué)會(SSR)成員委員會委員

15.高等教育學(xué)會醫(yī)學(xué)教育專委會理事

16.湖南省教指委醫(yī)學(xué)專業(yè)委員會副主任委員

17.湖南醫(yī)學(xué)教育科技學(xué)會副主任委員

18.Frontiers in Cell and Developmental Biology副主編

19.Asian Journal of Andrology編委


獲得的人才項目(榮譽)

1.湖湘高層次人才聚集工程-杰出創(chuàng)新人才,2018年,100萬元。

2.上海市教委-上海交通大學(xué)bwin必贏高峰學(xué)科計劃(雙百人計劃),2015年,100萬元。

3.上海高校特聘教授(東方學(xué)者),2012年,200萬元。

4.上海市浦江人才計劃,2011年,20萬元。


主持的科研項目14項)

1.國家自然科學(xué)基金重點項目:人精原干細胞自我更新與分化為精子細胞的分子機理研究,2013/01-2017/12,280萬元,項目負責人。

2.國家自然科學(xué)基金面上項目:SMC1A與YBX1互作影響HMGA2m5C穩(wěn)定性調(diào)控人精原干細胞命運決定的作用及機制研究,2025/01-2028/12,50萬元(直接費用),項目負責人。

3.國家自然科學(xué)基金面上項目:人類支持細胞重編程為精原干細胞及其分化為有功能的精子細胞的分子機制研究,2022/01-2025/12,58萬元(直接費用),項目負責人。

4.國家自然科學(xué)基金面上項目:PAK1調(diào)控人類精原干細胞自我更新與凋亡的作用及分子機制研究,2019/01-2022/12,60萬元(直接費用),項目負責人。

5.國家自然科學(xué)基金面上項目:非編碼小RNA調(diào)控正常與異常人精原干細胞自我更新與分化的作用及其機制研究,2017/01-2020/12,60萬元(直接費用),項目負責人。

6.國家自然科學(xué)基金面上項目:人精原干細胞誘導(dǎo)分化為成熟肝細胞及其信號轉(zhuǎn)導(dǎo)的研究,2012/01-2015/12,55萬元,項目負責人。

7.國家重點研發(fā)計劃課題:精子發(fā)生成熟障礙的表觀遺傳機制,2016/04-2021/06,557萬元,課題負責人。

8.國家重大科學(xué)研究計劃課題:減數(shù)分裂調(diào)控因子的篩查,2013/04-2014/08,248萬元,課題負責人。

9.國家重大科學(xué)研究計劃課題:精原干細胞命運決定的表觀遺傳調(diào)控,2014/08-2018/08,95.8萬元,子課題負責人。

10.湖南省重大專項課題:生殖細胞異常導(dǎo)致出生缺陷的機制研究,2019/10-2023/03,190萬元,課題負責人。

11.湖南省重點研發(fā)計劃項目:重大生殖疾病人源化動物模型的研究,2020/10-2022/09,50萬元,項目負責人。

12.湖南省教育廳優(yōu)勢特色學(xué)科重點項目:發(fā)育中的干細胞研究,2022/06-2024/06,70萬元,項目負責人。

13.湖南師范大學(xué)“生殖健康與轉(zhuǎn)化醫(yī)學(xué)”創(chuàng)新團隊,2023/07-2026/06,60萬元,項目負責人。

14.上海市科委重點項目:microRNA對人類精原干細胞生成精子的調(diào)控作用及其機制,2013/01-2015/12,40萬元,項目負責人。

代表性學(xué)術(shù)論文通訊作者第一作者已發(fā)表SCI收錄論文91篇,合計IF>450,*為通訊作者,#為第一作者):

1.Min Sun, Qingqing Yuan, Minghui Niu, Hong Wang, Liping Wen, Chencheng Yao, Jingmei Hou, Zheng Chen, Hongyong Fu, Fan Zhou, Chong Li, Shaorong Gao, Wei-Qiang Gao, Zheng Li,Zuping He*. Efficient Generation of Functional Haploid Spermatids From Human Germline Stem Cells by Three-Dimensional Induced System.Cell Death and Differentiation,2018, 25: 747-764. IF: 15.828

2.Yinghong Cui, Wei Chen,Li Du,Zuping He*.OIP5 interactswith NCK2to mediatehuman spermatogonial stem cellself-renewal and apoptosisthrough cell cyclins and cycle progression andits abnormality iscorrelated withmale infertility.Research, 2023, 6: 0162. IF: 11.0

3.Hong Wang, Ji Liu, Xiaojun Zhu, Bing Yang*,Zuping He*, Xudong Yao*.AZGP1P2/UBA1/RBM15 Cascade Mediates the Fate Determinations of Prostate Cancer Stem Cells and Promotes Therapeutic Effect of Docetaxel in Castration-Resistant Prostate Cancer via TPM1 m6A Modification.Research, 2023, 6:0252.IF: 11.0

4.Wei Chen,Yinghong Cui,Bang Liu,Chunyun Li,Li Du,Ruiling Tang,Lulu Qin,Yiqun Jiang,Jian Li,Xing Yu,Quanyuan He,Zuping He*.Hsa-miR-1908-3p Mediates the Self-Renewal and Apoptosis of Human Spermatogonial Stem Cells via Targeting KLF2,Molecular Therapy-Nucleic Acids, 2020, 20: 788-800.IF:10.18

5.Hongyong Fu, Wenhui Zhang, Qingqing Yuan, MinghuiNiu, Fan Zhou, QianqianQiu, Guoping Mao, Hong Wang, Liping Wen, Min Sun, Zheng Li,Zuping He*.PAK1 Promotes the Proliferation and Inhibits Apoptosis of Human Spermatogonial Stem Cells via PDK1/KDR/ZNF367 and ERK1/2 and AKT Pathways.Molecular Therapy-Nucleic Acid, 2018, 12: 769-786.IF:10.18

6.Hongyong Fu, Fan Zhou, Qingqing Yuan, Wenhui Zhang, QianqianQiu, Xing Yu,Zuping He*.MiRNA-31-5p Mediates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells via Targeting JAZF1 and Cyclin A2.Molecular Therapy-Nucleic Acid,2018, 14: 90-100.IF :10.18

7.Fan Zhou, Qingqing Yuan, Wenhui Zhang, MinghuiNiu, Hongyong Fu, QainqianQiu, Guiping Mao, Hong Wang, Liping Wen, Mujun Lu, Zheng Li,Zuping He*.MiR-663a Stimulates Proliferation and Suppresses Early Apoptosis of Human Spermatogonial Stem Cells by Targeting NFIX and Regulating Cell Cycle.Molecular Therapy-Nucleic Acid, 2018, 12: 319-336.IF :10.18

8.Chencheng Yao, Qingqing Yuan, MinghuiNiu,Hongyong Fu, Fan Zhou, Wenhui Zhang,Hong Wang, Liping Wen, Ligang Wu,Zheng Li*,Zuping He*.Distinct expression profiles and novel targets of microRNAs in human spermatogonia, pachytene spermatocytes and round spermatids betweenOA patients and NOA patients.Molecular Therapy-Nucleic Acids, 2017, 9: 182-194. IF :10.18

9.Hong Wang, Qingqing Yuan, MinghuiNiu, Wnihui Zhang, Liping Wen, Hongyong Fu, Fan Zhou,Zuping He*.Transcriptional regulation of P63 on the apoptosis of male germ cells and three stages of spermatogenesis in mice.Cell Death and Disease, 2018, 9(2):76. IF :9.685

10.Wei Liu,Li Du, Yinghong Cui,CaimeiHe,Zuping He*.WNT5Aregulatesthe proliferation, apoptosis and stemness of human stem Leydig cells via the β-catenin signaling pathway.Cellular and Molecular Life Sciences, 2024,81(1):93. IF :9.26

11.JunGao,ZhipengXu, Song W, Huang J,WeiLiu,Zuping He*,LeyeHe*.USP11 regulates proliferation and apoptosis of human spermatogonial stem cells via HOXC5-mediated canonical WNT/β-catenin signaling pathway.Cellular and Molecular Life Sciences, 2024,81(1):211. IF :9.26.

12.Zhipeng Xu,Cai Lv,Jun Gao,Yinghong Cui, Wei Liu,Zuping He*,Leye He*.LncRNA ACVR2B-as1interacts withALDOAto regulatethe self-renewaland apoptosisof human spermatogonial stem cellsby controllingglycolysis activity.Cellular and Molecular Life Sciences,accepted & in press. IF :9.26

13.Li Du, Wei Chen,Dong Zhang, Yinghong Cui,Zuping He*.The functions and mechanisms ofpiRNAsin mediating mammalian spermatogenesis and their applications in reproductive medicine.Cellularand Molecular Life Sciences, 2024,81(1):379. IF :9.26

14.Rui Zhou, Jingrouzi Wu, Bang Liu,Yiqun Jiang, Wei Chen, Jian Li, Quanyuan He,Zuping He*.The roles and mechanisms of Leydig cells and myoid cells in regulating spermatogenesis.Cellular and Molecular Life Sciences, 2019,76, 2681-2696. IF: 9.26

15.Wei Chen,Yinghong Cui,Chunyun Li,Caimei He,Li Du,Wei Liu,Zuping He*.KLF2 controls proliferation and apoptosis of human spermatogonial stem cells via targeting GJA1.iScience,2024 Jan 26;27(2):109024.IF :6.1

16.Wenhui Zhang, Wei Chen, Yinghong Cui,Liping Wen, Qingqing Yuan,Fan Zhou, Qianqian Qiu, Min Sun,Liping Wen, Zheng Li,Zuping He*Direct reprogramming of human Sertoli cells into male germline stem cells with the selfrenewal and differentiation potentials via overexpressing DAZL/DAZ2/BOULE genes,StemCellReports,2021, 16:2798-2812.IF: 7.765

17.Shi Yang, Ping Ping, Meng Ma, Peng Li, Ruhui Tian, Hao Yang, Yang Liu, Yuehua Gong, Zhenzhen Zhang, Zheng Li*,Zuping He*. Generation of haploid spermatids with fertilization and development capacity from human spermatogonial stem cells of cryptorchid patients.Stem Cell Reports, 2014, 3(4): 663-675. IF: 7.765

18.Li Du, Wei Chen, Chunyun Li, Yinghong Cui,Zuping He*.RNF144Bstimulatestheproliferation and inhibits the apoptosisof human spermatogonial stem cells via the FCER2/NOTCH2/HES1pathway and its abnormality is associated with azoospermia.Journal of Cellular Physiology,2022, 237(9):3565-3577. IF :6.51

19.Yinghong Cui,Mingqing Zhou,Quanyuan He,Zuping He*.Zbtb40Deficiency Leads to Morphological and Phenotypic Abnormalities of Spermatocytes and Spermatozoa and Causes Male Infertility.Cells,2023,12(9):1264.IF :7.666

20.Cailin Wan,Wei Chen,Yinghong Cui,Zuping He*.MAP4K4/JNK Signaling Pathway Stimulates Proliferation and Suppresses Apoptosis of Human Spermatogonial Stem Cells and Lower Level of MAP4K4 Is Associated with Male Infertility.Cells,2022, 11(23):3807. IF :7.666

21.Si Wu,Zixin Cheng,Ye Peng,Ying Cao,Zuping He*.GPx3 knockdown inhibits the proliferation and DNA synthesis and enhances the early apoptosis of human spermatogonial stem cells via mediating CXCL10 and cyclin B1.Frontiers in Cell and Developmental Biology, 2023,11:1213684.IF : 6.684

22.Bang Liu, Yinghong Cui, Wei Chen, Li Du, Chunyun Li,Cailin Wan,Zuping He*.Hsa-miR-100-3p Controls the Proliferation and DNA Synthesis and the Apoptosis of Human Sertoli Cells by Binding to SGK3.Frontiers in Cell and Developmental Biology, 2021,9:642916.IF : 6.684

23.Meng Ma, Shi Yang, Zhenzhen Zhang, Peng Li, Yuehua Gong, Linhong Liu, Yong Zhu, Ruhui Tian, Yufei Liu, Xiaobo Wang, Feng Liu, Lin He, Yang Liu, Hao Yang, Zheng Li*,Zuping He*.Sertoli cells from non-obstructive azoospermia and obstructive azoospermia patients show distinct morphology, raman spectrum and biochemical phenotype.Human Reproduction, 2013, 28(7):1863-1673.IF:6.918

24.Wei Chen, Yinghong Cu, Minqi Ning, Haorui Zhang, Chenjun Yin,Zuping He*.The mechanisms and functions of microRNAs in mediating the fate determinations of human spermatogonial stem cells and Sertoli cells.Seminars in Cell and Developmental Biology,2022, 121: 32-39. IF:7.727

25.Li Du, Wei Chen,Zixin Cheng, Si Wu, Jian He, Lu Han,Zuping He*,Wenbing Qin*.Novel Gene Regulation in Normal and Abnormal Spermatogenesis.Cells, 2021,10(3):666. IF:7.666

26.Hao Yang, Yang Liu, Yanan Hai, Yuehua Gong, Ying Guo, Shi Yang, Zhenzhen Zhang, Linhong Liu, Zheng Li, Wei-Qiang Gao,Zuping He*.Efficient conversion of mouse spermatogonial stem cells to phenotypic and functional dopaminergic neurons via PI3K/Akt and P21/Smurf2/Nolz1 pathway.Molecular Neurobiology,2015, 52(3):1654-1669.IF: 6.19

27.Fan Zhou,Wei Chen,Yinghong Cui,Bang Liu,Qingqing Yuan,Zheng Li,Zuping He*.miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7.Aging, 2021,12:25528-25546. IF: 5.682

28.QianqianQiu, Xing Yu, Chencheng Yao,YujunHao, Liqing Fan, Chunyi Li, Peng Xu,Geng An, Zheng Li,Zuping He*. FOXP3 pathogenic variants cause male infertility through affecting the proliferation and apoptosis of human spermatogonial stem cells.Aging, 2019, 11:12581-12599. IF: 5.682

29.Yanan Hai, Yun Liu, Jingmei Hou, Zhen Chen,Zuping He*. The roles and regulation of Sertoli cells in spermatogenesis.Seminars in Cell and Developmental Biology, 2014, 29:66-75. IF:7.727

30.Ying Guo, Yanan Hai, Chencheng Yao, Zheng Chen, JingmeiHou, Zheng Li,Zuping He*. Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation.Cell Communication and Signaling, 2015, 13: 20.

IF:7. 525

31.Zhenzhen Zhang, Yuehua Gong, Ying Guo, Yanan Hai, Hao Yang, Shi Yang, Yang Liu, Meng Ma, Linhong Liu, Zheng Li, Wei-Qiang Gao,Zuping He*. Direct transdifferentiation of spermatogonial stem cells to morphological, phenotypic and functional hepatocyte-like cells via the ERK1/2 and Smad2/3 signaling, pathways and the inactivation of cyclin A, cyclin B and cyclin E.Cell Signaling and Communications, 2013, 11:67. IF:7.525

32.Chao Yang, ChenchengYao, Ruhui Tian, Zijue Zhu, LiangyuZhao, Peng Li, Huixing Chen, Yuhua Huang, ErleiZhi, Yuehua Gong, YunjingXue, Hong Wang, Qingqing Yuan,Zuping He*, Zheng Li*. miR-202-3p Regulates Sertoli Cell Proliferation, Synthesis Function, and Apoptosis by Targeting LRP6 and Cyclin D1 of Wnt/β-Catenin Signaling.Molecular Therapy-Nucleic Acids, 2018,14: 1-19.IF :10.18

33.Ruhui Tian,Chencheng Yao,Chao Yang,Zijue Zhu,Chong Li,Erlei Zhi,Junlong Wang,Peng Li,Huixing Chen,Qingqing Yuan,Zuping He*,Zheng Li*.Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation.Stem Cell Research and Therapy,2019, 10(1):40.IF : 6.832

34.Dai Zhou,Jingyu Fan,Zhizhong Liu,Ruiling Tang,Xingming Wang,Hao Bo,Fang Zhu,Xueheng Zhao,Zenghui Huang,Liu Xing,Ke Tao,Han Zhang,Hongchuan Nie,Huan Zhang,Wenbing Zhu,Zuping He*,Liqing Fan*. TCF3 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells by Targeting PODXL.Frontiers in Cell and Developmental Biology, 2021,9: 695545. IF : 6.684

35.Mei Peng,Jintao Wu,Weifan Wang,Tianlong Liao,Simeng Xu,Di Xiao,Zuping He*,Xiaoping Yang*.Alpha-tocopherol enhances spermatogonial stem cell proliferation and restores mouse spermatogenesis by up-regulating BMI1.2023,10:1141964. IF : 6.59

36.Fang Zhu,Yang Luo,Hao Bo,Guanghui Gong,Ruiling Tang,Jingyu Fan,Huan Zhang,Gang Liu,Wenbing Zhu,Yueqiu Tan,Zuping He*,Liqing Fan*.Trace the profile and function of circular RNAs in Sertoli cell only syndrome.Genomics,2021, 113:1845-1854. IF: 5.736

37.Mingqing Zhou,Yinghong Cui,Shanru Zuo,Qiyao Peng,Yucong Liu,Xueguang Li,Yide Yang,Quanze He,Xing Yu,Junhua Zhou,Zuping He*,Quanyuan He.ZBTB40 is a telomere-associated protein and protects telomeres in human ALT cells.Journal of Biological Chemistry,2023, 299(9):105053.IF: 5.486

38.Z He#*,M Feng*.Activation, isolation, identification and culture of hepatic stem cells from porcine liver tissues.Cell Proliferation, 2011,44(6):558-566.IF:8.5

39.Zuping He#, Jiji Jiang, Maria Kokkinaki, Lin Tang, Wenxian Zeng, Ian Gallicano, Ina Dobrinski, Martin Dym. MiRNA-20 and MiRNA-106a Regulate Spermatogonial Stem Cell Renewal at the Post-Transcriptional Level via Targeting STAT3 and Ccnd1 2.Stem Cells, 2013, 31(10): 2205-2217. IF: 7.74

40.Zuping He#, Jiji Jiang, Maria Kokkinaki, Martin Dym. Nodal signaling via an autocrine pathway is required for proliferation of mouse spermatogonial stem/progenitor cells through smad2/3 and Oct-4 activation.Stem Cells,2009,27: 2580-2590.IF: 7.74

41.Zuping He#, Jiji Jiang, Maria Kokkinaki, NadyGolestaneh, Marie-Claude Hofmann, Martin Dym. Gdnf upregulates c-Fos transcription via the Ras/Erk1/2 pathway to promote mouse spermatogonial stem cell proliferation.Stem Cells,2008, 26:266-278.IF: 7.74

42.ZP He#,WQ Tan,YF Tang,HJ Zhang,MF Feng.Activation, isolation, identification and in vitro proliferation of oval cells from adult rat livers.Cell Proliferation, 2004,37(2):177-187.IF:8.5

科研獲獎:

1.湖南省自然科學(xué)獎二等獎,項目:人類精原干細胞自我更新與分化為精子細胞的分子機制研究。第一完成人何祖平

2.教育部科技進步獎二等獎,項目:精子發(fā)生障礙診療關(guān)鍵技術(shù)構(gòu)建及其臨床應(yīng)用。第二完成人:何祖平


國家發(fā)明專利(已授權(quán))

1.一種分離人精原干細胞的方法,專利號:ZL201110321182.9,何祖平,李錚,劉陽,劉建芳等。

2.一種人精原干細胞體外分化為功能精子細胞的三維誘導(dǎo)方法。專利號:ZL201610648584.2,何祖平,孫敏,袁青青,牛明輝,王洪,文麗平,付紅勇,周帆,李錚。

博士研究生、碩士研究生、博士后培養(yǎng):

1.在上海交通大學(xué)培養(yǎng)博士研究生7名,畢業(yè)博士研究生7名;培養(yǎng)碩士研究生4名,畢業(yè)碩士研究生4名;指導(dǎo)博士后4名,出站博士后4名。博士研究生導(dǎo)師考核結(jié)果為優(yōu)秀

2.在湖南師范大學(xué)培養(yǎng)博士研究生6名、碩士研究生10名;畢業(yè)博士研究生3名,畢業(yè)碩士研究生4名;指導(dǎo)博士后2名、訪問學(xué)者1名,出站博士后1名。

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