姓名：李亞敏

照片：

職稱：教授/主任護(hù)師

職務(wù)：湖南省人民醫(yī)院副院長(zhǎng)

研究生招生專業(yè)：護(hù)理（碩士學(xué)位）

電子郵箱：amin5433@163.com

簡(jiǎn)介：

李亞敏，女，博士，教授，博士生導(dǎo)師，湖南省人民醫(yī)院副院長(zhǎng)，中華護(hù)理學(xué)會(huì)精神衛(wèi)生護(hù)理專委會(huì)副主任委員，兼任中國(guó)醫(yī)學(xué)救援協(xié)會(huì)心理救援分會(huì)常務(wù)理事，中國(guó)研究型醫(yī)院學(xué)會(huì)護(hù)理研究分會(huì)常務(wù)理事，湖南省護(hù)理學(xué)會(huì)副理事長(zhǎng)，湖南省護(hù)理學(xué)會(huì)護(hù)理心理專委會(huì)主任委員，《中華護(hù)理雜志》《中國(guó)護(hù)理管理》雜志編委，《湘雅護(hù)理雜志》主編，教育部學(xué)位論文評(píng)審專家，國(guó)家自然科學(xué)基金同行評(píng)審專家。

主要從事精神衛(wèi)生與心理護(hù)理的研究及護(hù)理管理工作。主持國(guó)家自然科學(xué)基金項(xiàng)目2項(xiàng)；湖南省自然科學(xué)基金項(xiàng)目2項(xiàng)；湖南省重點(diǎn)研發(fā)計(jì)劃項(xiàng)目1項(xiàng)；中華護(hù)理學(xué)會(huì)項(xiàng)目1項(xiàng)；湖南省科技廳科技計(jì)劃項(xiàng)目1項(xiàng)；湖南省教育廳研究生改項(xiàng)目1項(xiàng)；中南大學(xué)研究生教改項(xiàng)目1項(xiàng)。

以第一作者/通訊作者在《Lancet Psychiatry》、《Nursing Ethics》、《Brain Behavior and Immunity》、《Obesity Reviews》、《中華護(hù)理雜志》、《中國(guó)臨床心理學(xué)雜志》等刊物發(fā)表論文100余篇；獲發(fā)明專利1項(xiàng)、實(shí)用新型專利5項(xiàng)；主編國(guó)家衛(wèi)健委十四五規(guī)劃教材《護(hù)理心理學(xué)》、教育護(hù)理學(xué)十三五規(guī)劃教材《護(hù)理學(xué)導(dǎo)論》等教材6本，副主編教材5本。

社會(huì)（學(xué)術(shù)）兼職：

1.中華護(hù)理學(xué)會(huì)精神衛(wèi)生護(hù)理專業(yè)委員會(huì)副主任委員

2.中國(guó)醫(yī)學(xué)救援協(xié)會(huì)心理救援分會(huì)常務(wù)理事

3.中國(guó)研究型醫(yī)院護(hù)理學(xué)研究分會(huì)常務(wù)理事

4.湖南省護(hù)理學(xué)會(huì)理事長(zhǎng)

5.湖南省護(hù)理學(xué)會(huì)心理護(hù)理專委會(huì)主任委員

6.《中華護(hù)理雜志》編委

7.《中國(guó)護(hù)理管理》雜志編委

8.《湘雅護(hù)理雜志》主編

9.教育部學(xué)位論文評(píng)審專家

10.國(guó)家自然科學(xué)基金同行評(píng)審專家

所獲獎(jiǎng)勵(lì)（榮譽(yù)）：

1.湖南省優(yōu)秀科技工作者

2.湖南省三八紅旗手

3.全國(guó)護(hù)理學(xué)專家學(xué)術(shù)影響力百?gòu)?qiáng)排名第10名

4.中南大學(xué)湘雅二醫(yī)院“優(yōu)秀研究生導(dǎo)師”

5.中南大學(xué)湘雅二醫(yī)院“師德先進(jìn)個(gè)人”

主持課題：

1.國(guó)家自然科學(xué)基金面上項(xiàng)目：基于PET成像蘿卜硫素調(diào)控小膠質(zhì)細(xì)胞神經(jīng)炎癥治療ASD機(jī)制研究

2.國(guó)家自然科學(xué)基金面上項(xiàng)目：蘿卜硫素抑制NF-κB信號(hào)通路調(diào)控小膠質(zhì)細(xì)胞與星形膠質(zhì)細(xì)胞突觸修剪功能治療ASD作用及機(jī)制研究

3.湖南省自然科學(xué)基金面上項(xiàng)目：蘿卜硫素對(duì)ASD腸道微生物的影響及分子機(jī)制研究

4.湖南省自然科學(xué)基金面上項(xiàng)目：小膠質(zhì)細(xì)胞與星形膠質(zhì)細(xì)胞過度激活致突觸修剪異常與ASD發(fā)病關(guān)聯(lián)及機(jī)制研究

5.湖南省重點(diǎn)研發(fā)計(jì)劃項(xiàng)目：精神健康急救關(guān)鍵技術(shù)研發(fā)與推廣

6.中華護(hù)理學(xué)會(huì)面上項(xiàng)目：中國(guó)護(hù)士心理健康隊(duì)列研究

以第一/通訊作者發(fā)表的科研論文：

[1]ZHANG H, LI Y, ZENG Y, et al. Endothelin-1 Downregulates Angiotensin-Converting Enzyme-2 Expression in Human Bronchial Epithelial Cells [J]. Pharmacology, 2013, 91(5-6): 297-304.

[2]LEI X-Y, XIAO L-M, LIU Y-N, et al. Prevalence of Depression among Chinese University Students: A Meta-Analysis [J]. Plos One, 2016, 11(4):

[3]LI Y-M, PENG J, LI L-Z. Coffee consumption associated with reduced risk of oral cancer: a meta-analysis [J]. Oral Surgery Oral Medicine Oral Pathology Oral Radiology, 2016, 121(4): 381-U150.

[4]SHEN Y, OU J, LIU M, et al. Altered plasma levels of chemokines in autism and their association with social behaviors [J]. Psychiatry Research, 2016, 244(300-305.

[5]ZENG Y-N, LI Y-M. Secondhand smoke exposure and mental health in adults: a meta-analysis of cross-sectional studies [J]. Social Psychiatry and Psychiatric Epidemiology, 2016, 51(9): 1339-1348.

[6]LI Y-J, LI Y-M, XIANG D-X. Supplement intervention associated with nutritional deficiencies in autism spectrum disorders: a systematic review [J]. European Journal of Nutrition, 2018, 57(7): 2571-2582.

[7]LI Y-M, SHEN Y-D, LI Y-J, et al. Maternal dietary patterns, supplements intake and autism spectrum disorders A preliminary case-control study [J]. Medicine, 2018, 97(52):

[8]LIAO X, LEI X, LI Y. Stigma among parents of children with autism: A literature review [J]. Asian Journal of Psychiatry, 2019, 45(88-94.

[9]ZENG Y, LIN R, LIU L, et al. Ambient air pollution exposure and risk of depression: A systematic review and meta-analysis of observational studies [J]. Psychiatry Research, 2019, 276(69-78.

[10]CHEN Q, LIANG M, LI Y, et al. Mental health care for medical staff in China during the COVID-19 outbreak [J]. Lancet Psychiatry, 2020, 7(4): E15-E16.

[11]CHEN R, WANG Y, LIU L, et al. A qualitative study of how self-harm starts and continues among Chinese adolescents [J]. Bjpsych Open, 2020, 7(1):

[12]FU X, YANG J, LIAO X, et al. Parents' Attitudes Toward and Experience of Non-Suicidal Self-Injury in Adolescents: A Qualitative Study [J]. Frontiers in Psychiatry, 2020, 11(

[13]LI Y-J, XIE X-N, LEI X, et al. Global prevalence of obesity, overweight and underweight in children, adolescents and adults with autism spectrum disorder, attention-deficit hyperactivity disorder: A systematic review and meta-analysis [J]. Obesity Reviews, 2020, 21(12):

[14]LIAO X, LI Y. Economic burdens on parents of children with autism: a literature review [J]. Cns Spectrums, 2020, 25(4): 468-474.

[15]LIAO X, LI Y. Genetic associations between voltage-gated calcium channels and autism spectrum disorder: a systematic review [J]. Molecular Brain, 2020, 13(1):

[16]LIAO X, LI Y. Nuclear Factor Kappa B in Autism Spectrum Disorder: A Systematic Review [J]. Pharmacological Research, 2020, 159(

[17]LIAO X, LIU Y, FU X, et al. Postmortem Studies of Neuroinflammation in Autism Spectrum Disorder: a Systematic Review [J]. Molecular Neurobiology, 2020, 57(8): 3424-3438.

[18]LIAO X, YANG J, WANG H, et al. Microglia mediated neuroinflammation in autism spectrum disorder [J]. Journal of Psychiatric Research, 2020, 130(167-176.

[19]LIU H, LI X, CHEN Q, et al. Illness perception, mood state and disease-related knowledge level of COVID-19 family clusters, Hunan, China [J]. Brain Behavior and Immunity, 2020, 88(30-31.

[20]TIAN Y, YUE Y, WANG J, et al. Workplace violence against hospital healthcare workers in China: a national WeChat-based survey [J]. Bmc Public Health, 2020, 20(1):

[21]YANG J, FU X, LIAO X, et al. Effects of gut microbial-based treatments on gut microbiota, behavioral symptoms, and gastrointestinal symptoms in children with autism spectrum disorder: A systematic review [J]. Psychiatry Research, 2020, 293(

[22]YANG J, FU X, LIAO X, et al. Nrf2 Activators as Dietary Phytochemicals Against Oxidative Stress, Inflammation, and Mitochondrial Dysfunction in Autism Spectrum Disorders: A Systematic Review [J]. Frontiers in Psychiatry, 2020, 11(

[23]YANG J, FU X, LIAO X, et al. Association of problematic smartphone use with poor sleep quality, depression, and anxiety: A systematic review and meta-analysis [J]. Psychiatry Research, 2020, 284(

[24]YANG J, HU H, LI Y. EFFECT OF DUAL-TRACK INTERACTIVE NURSING INTERVENTION MODEL ON ANXIETY AND DEPRESSION IN PATIENTS WITH CORONARY HEART DISEASE [J]. Psychiatria Danubina, 2020, 32(2): 197-204.

[25]CHEN H, LI Y, WANG W, et al. Reliability and validity of the multidimensional dyspnea profile in hospitalized Chinese patients with respiratory diseases [J]. SAGE open medicine, 2021, 9(2050312120965336-2050312120965336.

[26]FU X, YANG J, LIAO X, et al. Parents' and medical staff's experience of adolescents with suicide-related behaviors admitted to a general hospital in China: qualitative study [J]. Bmc Psychiatry, 2021, 21(1):

[27]HE Q, LI Y, ZHOU X, et al. The combination of fibrinogen concentrations and the platelet-to-lymphocyte ratio predicts survival in patients with advanced lung adenocarcinoma treated with EGFR-TKIs [J]. Journal of International Medical Research, 2021, 49(4):

[28]LI S, LI J, PENG L, et al. Cost-Effectiveness of Frontline Treatment for Advanced Renal Cell Carcinoma in the Era of Immunotherapies [J]. Frontiers in Pharmacology, 2021, 12(

[29]LI S, LI J, PENG L, et al. Cost-Effectiveness of Lorlatinib as a First-Line Therapy for Untreated Advanced Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer [J]. Frontiers in Oncology, 2021, 11(

[30]LI S, LI J, PENG L, et al. Cost-effectiveness of Triple Therapy vs. Biologic Treatment Sequence as First-line Therapy for Rheumatoid Arthritis Patients after Methotrexate Failure [J]. Rheumatology and Therapy, 2021, 8(2): 775-791.

[31]LI S, LI J, PENG L, et al. Cost-Effectiveness of Baricitinib for Patients with Moderate-to-Severe Rheumatoid Arthritis After Methotrexate Failed in China [J]. Rheumatology and Therapy, 2021, 8(2): 863-876.

[32]LI S, LI J, PENG L, et al. Cost-Effectiveness of Nivolumab Plus Cabozantinib Versus Sunitinib as a First-Line Treatment for Advanced Renal Cell Carcinoma in the United States [J]. Frontiers in Pharmacology, 2021, 12(

[33]LI S, LI J, PENG L, et al. First-line Daratumumab in Addition to Chemotherapy for Newly Diagnosed Multiple Myeloma Patients Who are Transplant Ineligible: A Cost-Effectiveness Analysis [J]. Clinical Therapeutics, 2021, 43(7): 1253-+.

[34]LIANG M, LI Y, CHEN Q, et al. The Difficulties and Mental Health Intervention Need of Doctors and Nurses in Biological Emergencies: A Qualitative Study [J]. Frontiers in Psychiatry, 2021, 12(

[35]LIU R, DONG H, WANG Y, et al. Sleep Problems of Children with Autism May Independently Affect Parental Quality of Life [J]. Child Psychiatry & Human Development, 2021, 52(3): 488-499.

[36]SHEN Y, LI Y, SHI L, et al. Autism spectrum disorder and severe social impairment associated with elevated plasma interleukin-8 [J]. Pediatric Research, 2021, 89(3): 591-597.

[37]TIAN Y, YUE Y, LIAO X, et al. Mental health service use and its associated factors among nurses in China: a cross-sectional survey [J]. Peerj, 2021, 9(

[38]WANG H, DENG S, FAN X, et al. Research Trends and Hotspots of Extracorporeal Membrane Oxygenation: A 10-Year Bibliometric Study and Visualization Analysis [J]. Frontiers in Medicine, 2021, 8(

[39]WANG L, NORMAN I, XIAO T, et al. Psychological First Aid Training: A Scoping Review of Its Application, Outcomes and Implementation [J]. International Journal of Environmental Research and Public Health, 2021, 18(9):

[40]WANG Y, LIN J, ZENG Y, et al. Effects of Sleep Disturbances on Behavioral Problems in Preschool Children With Autism Spectrum Disorder [J]. Frontiers in Psychiatry, 2021, 11(

[41]YANG Y, LIN J, LU X, et al. Anesthesia, sex and miscarriage history may influence the association between cesarean delivery and autism spectrum disorder [J]. Bmc Pediatrics, 2021, 21(1):

[42]ZHAI M, LONG J, LIU S, et al. The burden of liver cirrhosis and underlying etiologies: results from the global burden of disease study 2017 [J]. Aging-Us, 2021, 13(1): 279-300.

[43]ZHAI M, ZHANG D, LONG J, et al. The global burden of thyroid cancer and its attributable risk factor in 195 countries and territories: A systematic analysis for the Global Burden of Disease Study [J]. Cancer Medicine, 2021, 10(13): 4542-4554.

[44]CHEN Z, PENG K, LIU X, et al. Association between high burn-out and workplace violence among healthcare workers in China: a WeChat-based survey [J]. Bmj Open, 2022, 12(11):

[45]DENG C, XIE Y, LIU Y, et al. Aromatherapy Plus Music Therapy Improve Pain Intensity and Anxiety Scores in Patients With Breast Cancer During Perioperative Periods: A Randomized Controlled Trial [J]. Clinical Breast Cancer, 2022, 22(2): 115-120.

[46]HUANG S, LIAO X, WU J, et al. The Microglial membrane receptor TREM2 mediates exosome secretion to promote phagocytosis of amyloid-beta by microglia [J]. Febs Letters, 2022, 596(8): 1059-1071.

[47]LI Y, LIU Y, ZHANG L, et al. Acupuncture for Pain and Function in Patients with Nonspecific Low Back Pain: Study Protocol for an Up-to-Date Systematic Review and Meta-Analysis [J]. Journal of Pain Research, 2022, 15(1379-1387.

[48]LI Z, LI J, LI Y, et al. Anxiety and depression in the post-pandemic era: concerns about viral mutation and re-outbreak [J]. Bmc Psychiatry, 2022, 22(1):

[49]OU J, SMITH R C, TOBE R H, et al. Efficacy of Sulforaphane in Treatment of Children with Autism Spectrum Disorder: A Randomized Double-Blind Placebo-Controlled Multi-center Trial [J]. Journal of Autism and Developmental Disorders, 2022,

[50]TIAN Y, YUE Y, YANG J, et al. Sociodemographic, occupational, and personal factors associated with sleep quality among Chinese medical staff: A web-based cross-sectional study [J]. Frontiers in Public Health, 2022, 10(

[51]WANG L, NORMAN I, XIAO T, et al. Evaluating a Psychological First Aid Training Intervention (Preparing Me) to Support the Mental Health and Wellbeing of Chinese Healthcare Workers During Healthcare Emergencies: Protocol for a Randomized Controlled Feasibility Trial [J]. Frontiers in Psychiatry, 2022, 12(

[52]XIAO Y, LI Y, CAI Z, et al. Investigation on the Correlation of Anxiety Degree with Family Atmosphere in Children with Precocious Puberty [J]. Emergency Medicine International, 2022, 2022(

[53]XIE C, LI L, LI Y. Learned Helplessness in Renal Dialysis Patients: Concept Analysis with an Evolutionary Approach [J]. Patient Preference and Adherence, 2022, 16(2301-2312.

[54]YANG J, CHEN Y, YAO G, et al. Key factors selection on adolescents with non-suicidal self-injury: A support vector machine based approach [J]. Frontiers in Public Health, 2022, 10(

[55]YANG Y, SHEN Y, LIN J, et al. Association between history of miscarriage and autism spectrum disorder [J]. European Archives of Psychiatry and Clinical Neuroscience, 2022,

[56]YE M, CHEN S-H, LI X-T, et al. Effects of Disease-Related Knowledge on Illness Perception and Psychological Status of Patients With COVID-19 in Hunan, China [J]. Disaster Medicine and Public Health Preparedness, 2022, 16(4): 1415-1422.

[57]ZHAI M, JIANG Q, LIU S, et al. DALY trend and predictive analysis of COPD in China and its provinces: Findings from the global burden of disease study [J]. Frontiers in Public Health, 2022, 10(

[58]ZHANG C, SHI L, TIAN T, et al. Associations Between Academic Stress and Depressive Symptoms Mediated by Anxiety Symptoms and Hopelessness Among Chinese College Students [J]. Psychology Research and Behavior Management, 2022, 15(547-556.

[59]LI L, LU S, XIE C, et al. Stigmatizing attitudes toward mental disorders among non-mental health nurses in general hospitals of China: a national survey [J]. Frontiers in Psychiatry, 2023, 14(

[60]LI L, XIE C, LI Y. Factors Associated with Self-Management of Peritoneal Dialysis Patients in Urumqi of Xinjiang of China: A Cross-Sectional Survey [J]. Patient Preference and Adherence, 2023, 17(1573-1589.

[61]LI S, CHEN Z, YONG Y, et al. Effectiveness of acceptance and commitment therapy-based interventions for improving the psychological health of parents of children with special health care needs: A systematic review and meta-analysis [J]. Comprehensive psychiatry, 2023, 127(152426-152426.

[62]LI S, YONG Y, LI Y, et al. Cognitive-Based Interventions for Improving Psychological Health and Well-Being for Parents of Children with Developmental Disabilities: A Systematic Review and Meta-analysis [J]. Journal of Autism and Developmental Disorders, 2023,

[63]LI W, LI X, CHEN T, et al. Factors affecting lung cancer patients' intention to perform early postoperative exercise: a qualitative study based on theory of planned behavior [J]. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023, 31(12): 649-649.

[64]LI X, CHE C C, LI Y, et al. The mediating role of coping styles in the relationship between second victim experience and professional quality of life among nurses: a cross-sectional study [J]. Bmc Nursing, 2023, 22(1):

[65]LI X, LIU S, TIAN Y, et al. Challenges for psychiatric nurses working with non-suicidal self-injury adolescents: a qualitative study [J]. Bmc Nursing, 2023, 22(1):

[66]LIANG M, CHEN Q, GUO J, et al. Mental health first aid improves mental health literacy among college students: A meta-analysis [J]. Journal of American College Health, 2023, 71(4): 1196-1205.

[67]LIAO X, CHEN M, LI Y. The glial perspective of autism spectrum disorder convergent evidence from postmortem brain and PET studies [J]. Frontiers in Neuroendocrinology, 2023, 70(

[68]LONG Y, WANG Y, SHEN Y, et al. Minocycline and antipsychotics inhibit inflammatory responses in BV-2 microglia activated by LPS via regulating the MAPKs/ JAK-STAT signaling pathway [J]. Bmc Psychiatry, 2023, 23(1):

[69]XIE C, LI L, LI Y. Trajectories of Learned Helplessness in Maintenance Haemodialysis Patients and Their Predictive Effects on Self-Management: A Latent Growth Mixture Modeling Approach [J]. Psychology Research and Behavior Management, 2023, 16(351-361.

[70]XIE C, LI L, LI Y. Humor-based interventions for patients undergoing hemodialysis: A scoping review [J]. Patient Education and Counseling, 2023, 114(

[71]XIE C, LI L, LI Y. "Alive Day is the Day": A Qualitative Study of Experiences of Learned Helplessness in Maintenance Haemodialysis Patients [J]. Risk Management and Healthcare Policy, 2023, 16(231-245.

[72]XIE C, LI L, ZHOU L, et al. Mediating role of learned helplessness' components in the association between health literacy/social support and self-management among maintenance haemodialysis patients in Changsha, China: a cross-sectional study [J]. Bmj Open, 2023, 13(8):

[73]XIE C, ZHOU L, SUN C, et al. The cross-cultural adaptation and psychometric evaluation of a learned helplessness scale for maintenance hemodialysis patients in China (LHS-MHD-C) [J]. Research in Nursing & Health, 2023, 46(2): 251-262.

[74]XIE J, LI S, LI Y, et al. Cost-effectiveness of sacituzumab govitecan versus chemotherapy in patients with relapsed or refractory metastatic triple-negative breast cancer [J]. Bmc Health Services Research, 2023, 23(1):

[75]YANG J, SHEN Y, TIAN Y, et al. Investigating and comparing the psychometric properties of the Chinese Mandarin version of social responsiveness scale-2 and its shortened version in preschool-age children with autism spectrum disorder [J]. Asian Journal of Psychiatry, 2023, 79(

[76]YU Q, WANG H, TIAN Y, et al. Moral courage, job-esteem, and social responsibility in disaster relief nurses [J]. Nursing Ethics, 2023,

[77]ZHAI M, LI Y, LI Y. Choice of evaluation time points and improvement of web-based transitional care programme [J]. Journal of Clinical Nursing, 2023, 32(15-16): 5396-5397.