名字：李曉丹

照片：

職稱：副教授

專業(yè)：免疫、微生物

電子郵箱：lxd@live.cn

通訊地址：湖南省長沙市岳麓區(qū)桐梓坡路371號bwin必贏醫(yī)學檢驗系，郵編410013

簡介：

李曉丹，碩士生導師，2010年畢業(yè)于中國醫(yī)科大學，獲醫(yī)學學士學位；2015年畢業(yè)于中國科學院武漢病毒研究所，獲理學博士學位，現(xiàn)任檢驗系微生物教研室講師。主持有國家自然科學基金、湖南省自然科學基金、湖南省教育廳基金等研究項目。

代表性學術(shù)論文：

1. Shi YJ, Li JQ, Zhang HQ, Deng CL, Zhu QX, Zhang B(*),Li XD(*). A high throughput antiviral screening platform for alphaviruses based on Semliki Forest virus expressing eGFP reporter gene. Virol Sin. 2023 Aug;38(4):585-594

2. Zhang ZR (#), Zhang YN (#), Zhang HQ (#), Zhang QY, Li N, Li Q, Deng CL, Zhang B,Li XD(*), Ye HQ(*). Berbamine hydrochloride potently inhibits SARS-CoV-2 infection by blocking S protein-mediated membrane fusion.PLoS Negl Trop Dis. 2022 Apr 25;16(4):e0010363.

3.Li JQ (#), Zhang ZR (#), Zhang HQ (#), Zhang YN (#), Zeng XY, Zhang QY, Deng CL,Li XD(*), Zhang B (*), Ye HQ (*). 2021. Intranasal delivery of replicating mRNA encoding neutralizing antibody against SARS-CoV-2 infection in mice.Signal Transduct Target Ther6:369.

4. Zhang QY(#), Deng CL(#), Liu J(#), Li JQ(#), Zhang HQ(#), Li N(#), Zhang YN(#),Li XD(*), Zhang B(*), Xu Y(*), Ye HQ(*), 2021. SARS-CoV-2 replicon for high-throughput antiviral screening. 2020. J Gen Virol. 102(5).

5. Zhang YN, Liu SQ, Deng CL, Yuan ZM, Zhang B,Li XD(*), Ye HQ (*). 2021. Development and Characterization of SYBR Green I Based RT-PCR Assay for Detection of Omsk Hemorrhagic Fever Virus.Virol Sin36:1644-1647.

6. Zhang ZR(#), Zhang YN(#),Li XD(#), Zhang HQ, Xiao SQ, Deng F, Yuan ZM, Ye HQ(*), Zhang B. (*)2020. A cell-based large-scale screening of natural compounds for inhibitors of SARS-CoV-2. Signal Transduct Target Ther 5:218.

7. Zhang YN(#), Zhang QY(#),Li XD(#), Xiong J, Xiao SQ, Wang Z, Zhang ZR, Deng CL, Yang XL, Wei HP, Yuan ZM, Ye HQ(*), Zhang B(*).2020. Gemcitabine, lycorine and oxysophoridine inhibit novel coronavirus (SARS-CoV-2) in cell culture. Emerg Microbes Infect 9:1170-1173.

8. Zhang YN(#),Li XD(#), Zhang ZR(#), Zhang HQ, Li N, Liu J, Li JQ, Zhang HJ, Wang ZJ, Shen S, Shi ZL, Wei HP, Yuan ZM, Ye HQ(*), Zhang B(*).2020. A mouse model for SARS-CoV-2 infection by exogenous delivery of hACE2 using alphavirus replicon particles.Cell Resdoi:10.1038/s41422-020-00405-5:1-3.

9.Li XD, Deng CL, Yuan ZM, Ye HQ, Zhang B(*).2020. Different Degrees of 5'-to-3' DAR Interactions Modulate Zika Virus Genome Cyclization and Host-Specific Replication.J Virol94.

10.Li XD, Zhang HQ, Zhang YN, Li J, Wang Z, Deng CL, Jardim ACG, Terzian ACB, Nogueira ML, Zhang B.2019. Development of a rapid antiviral screening assay based on eGFP reporter virus of Mayaro virus.Antiviral Res168:82-90.

12.趙亭亭，徐葉，廖旻晶，劉如石，李曉丹(*).寨卡病毒NS1蛋白的原核表達和單克隆抗體的制備，2019，中國人獸共患病學報，35(03).