名字:張慧慧
照片:
職稱:副教授
研究生招生專業(yè):免疫學,醫(yī)學技術
電子郵箱:zhanghh87@hunnu.edu.cn
通訊地址:至謹樓331
簡介:
張慧慧,副教授,碩士生導師。2009年6月畢業(yè)于山東師范大學生命科學學院,獲學士學位;2014年6月畢業(yè)于武漢大學生命科學學院,獲博士學位。目前從事腫瘤發(fā)生的分子機制研究。
獲得的教學表彰
湖南師范大學第20屆青年教師課堂教學競賽二等獎
主持課題項目:
1.國家自然科學基金青年項目(81602450),2017.01-2019.12
2.湖南省自然科學基金青年基金項目(2018JJ3337),2018.01-2020.12
3.湖南省衛(wèi)生健康委項目(C2016045),2016.01-2017.12
4.湖南省衛(wèi)生健康委課題 (202202084830),2022.1-2024.12
社會兼職
湖南省生物化學與分子生物學學會青年委員
代表性學術論文:
1.Huang L, Zhang AQ, Tang CY, Wei JM, Li M, Yuan SS,Zhang HH#, Zhang X#. Identification of potential prognostic markers for lung adenocarcinoma using comprehensive analysis. Mol Med Rep. 2023 Aug;28(2):149. doi: 10.3892/mmr.2023.13036..
2.Zhang HH, Li C, Ren JW, Liu L, Du XH, Gao J, Liu T, Li SZ. OTUB1 facilitates bladder cancer progression by stabilizing ATF6 in response to endoplasmic reticulum stress. Cancer Sci. 2021 Jun;112(6):2199-2209. doi: 10.1111/cas.14876.
3.Zhang HH, Cao RH, Zeng F, Fan W, Guo L, Ma Q, Ke S. Bivalent β-Carbolines Inhibit Colorectal Cancer Growth through Inducing Autophagy. Chem Pharm Bull (Tokyo). 2021;69(11):1104-1109. doi: 10.1248/cpb.c21-00588.
4.Zhang HH, Li YD, Xun Y, Liu H, Wei CX, Wang H, Yang XP, Yuan SS, Liu N, Xiang SL. Polydatin protects neuronal cells from hydrogen peroxide damage by activating CREB/Ngb signaling. Mol Med Rep. 2022 Jan;25(1):9. doi: 10.3892/mmr.2021.12525.
5.Zhang MH,Zhang HH, Du XH, Gao J, Li C, Shi HR, Li SZ. UCHL3 promotes ovarian cancer progression by stabilizing TRAF2 to activate the NF-κB pathway. Oncogene. 2020 Jan;39(2):322-333. doi: 10.1038/s41388-019-0987-z.
6.Zhao H, Pan WM.,Zhang HH, Song, Y, Chen J, Xiang Y, Gu B, Li SZ., Du RL, Zhang XD. (2019). Cancer testis antigen 55 deficiency attenuates colitis-associated colorectal cancer by inhibiting NF-κB signaling. Cell Death Dis. 2019 Apr 3;10(4):304. doi: 10.1038/s41419-019-1537-x.
7.Li, S.Z., Shu, Q.P., Song, Y.,Zhang, H.H., Liu, Y., Jin, B.X., Liuyu, T.Z., Li, C., Huang, X.C., Du, R.L., et al.(2019). Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response. Nature communications10, 3233.
8.Zhao, H., Pan, W.M.,Zhang, H.H., Song, Y., Chen, J., Xiang, Y., Gu, B., Li, S.Z., Du, R.L., and Zhang, X.D. (2019). Cancer testis antigen 55 deficiency attenuates colitis-associated colorectal cancer by inhibiting NF-kappaB signaling. Cell death & disease10, 304.
9.Zhang, H.H., Li, S.Z., Zhang, Z.Y., Hu, X.M., Hou, P.N., Gao, L., Du, R.L., and Zhang, X.D. (2014). Nemo-like kinase is critical for p53 stabilization and function in response to DNA damage. Cell death and differentiation21, 1656-1663.