姓名：李俊男
照片：
職稱：講師
電子郵箱：lijunnan0509@126.com
個(gè)人簡(jiǎn)介：李俊男，女，漢族，碩士生導(dǎo)師。2023年畢業(yè)于澳門大學(xué)，獲得生物醫(yī)藥專業(yè)博士學(xué)位, 同年7月加入bwin必贏藥學(xué)系和“小分子靶向藥物研究與創(chuàng)制”湖南省重點(diǎn)實(shí)驗(yàn)室?，F(xiàn)主持湖南省自然科學(xué)青年基金項(xiàng)目一項(xiàng)。主要從事肺癌腫瘤耐藥的治療及其機(jī)制的研究，通過(guò)建立EGFR-TKIs耐藥細(xì)胞系，對(duì)耐藥機(jī)制進(jìn)行深入探索并且設(shè)計(jì)不同的聯(lián)合手段進(jìn)行逆轉(zhuǎn)耐藥的研究。近年在Drug Resistance Updates, Cellular and Molecular Life Sciences等國(guó)際知名期刊發(fā)表SCI論文數(shù)篇，其中第一作者（包含共同一作）共計(jì)5篇。
代表學(xué)術(shù)性論文：
(1)Junnan Li;Lipeng Zhu; Hang Fai Kwok; Nanotechnology-based approaches overcome lung cancer drug resistance through diagnosis and treatment, Drug Resistance Updates, 2023, 66: 100904
(2)Junnan Li;Pengchen Chen; Qiushuang Wu; Libin Guo; Ka Weng Leong; Kin Iong Chan; Hang Fai Kwok; A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis, Cellular and Molecular Life Sciences, 2022, 79(12): 614
(3)Junnan Li;Hongwei Du; Meishuang Zhang; Zhi Zhang; Fei Teng; Yali Zhao; Wenyou Zhang; Yang Yu; Linjing Feng; Xinming Cui; Ming Zhang; Tzongshi Lu; Fengying Guan; Li Chen; Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA2β/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 β-cells, International Journal of Biological Sciences, 2019, 15(7): 1533-1545
(4)Junnan Li;Hang Fai Kwok; Current Strategies for Treating NSCLC: From Biological Mechanisms to Clinical Treatment, Cancers, 2020, 12(6): 1587
(5) Lipeng Zhu#;Junnan Li#;Ziang Guo; Hang Fai Kwok; Qi Zhao; Synergistic combination of targeted nano-nuclear-reactors and anti-PD-L1 nanobodies evokes persistent T cell immuneactivation for cancer immunotherapy, Journal of Nanobiotechnology, 2022, 20(1): 521
(6) Qiushuang Wu, ChenPeng Chen,Junnan Li,et al. Inhibition of bladder cancer growth with Homoharringtonine by inactivating integrin α5/β1-FAK/Src axis: A novel strategy for drug application. Pharmacological Research 188: 106654.
(7) Yang Yu, Linjing Feng,Junnan Li,Xiaoxin Lan,et al. The alteration of autophagy and apoptosis in the hippocampus of rats with natural aging-dependent cognitive deficits. Behavioural Brain Research. 2017;334:155-162.
(8)李俊男，于洋，杜紅偉胰島β細(xì)胞退分化在β細(xì)胞功能衰竭中的作用 中國(guó)病理生理雜志2018
