名字:張霞
照片:
職稱:講師
招生專業(yè):醫(yī)學(xué)檢驗(yàn)技術(shù)、免疫學(xué)
聯(lián)系電話:17608407389
電子郵箱:zx717@hunnu.edu.cn
通訊地址:湖南省長(zhǎng)沙市岳麓區(qū)桐梓坡路371號(hào),bwin必贏,郵編:410013
簡(jiǎn)介:
張霞,醫(yī)學(xué)博士,2006年獲得山東大學(xué)臨床醫(yī)學(xué)學(xué)士學(xué)位,2011年獲得山東大學(xué)免疫學(xué)博士學(xué)位。后在青島bwin必贏附屬煙臺(tái)毓璜頂醫(yī)院檢驗(yàn)中心工作5年,主要從事血液病的輔助診斷。2016年進(jìn)入bwin必贏免疫教研室工作。 主要從事腫瘤、炎癥性疾病領(lǐng)域的研究。
主持的科研項(xiàng)目:
(1)國(guó)家自然科學(xué)基金青年項(xiàng)目,PDCD4抑制細(xì)胞自噬對(duì)卵巢癌惡性行為的影響及分子機(jī)制,81202069,2013.1-2015.12,23萬(wàn)元
(2)湖南省自然科學(xué)基金青年項(xiàng)目, 2018JJ3365, PDCD4在腫瘤相關(guān)成纖維細(xì)胞促進(jìn)卵巢癌上皮間質(zhì)化中的作用及機(jī)制研究, 2018/01 -2020/12, 5萬(wàn)元
(3)湖南省教育廳重點(diǎn)項(xiàng)目, 20A308,程序性細(xì)胞死亡4對(duì)急性B淋巴細(xì)胞白血病的抑制作用研究, 2021/01-2023/12, 6萬(wàn)元
(4)湖南省衛(wèi)生健康委一般資助項(xiàng)目, 202102071747,抑癌基因PDCD4對(duì)慢性粒細(xì)胞白血病的作用研究, 2021/01-2023/12, 4萬(wàn)元
代表性學(xué)術(shù)論文:
1.Liang Huang, Anqi Zhang, Chunyan Tang, Jinmei Wei, Miao Li, Shishan Yuan, Huihui Zhang, Xia Zhang*. Identification of potential prognostic markers for lung adenocarcinoma using comprehensive analysis. Mol Med Rep. 2023 Aug;28(2):149.
2.龍馨妍;何澤詔;彭鵬;李濤;張慧慧;袁仕善;張霞* ;程序性細(xì)胞死亡蛋白4調(diào)控K562細(xì)胞活力和 凋亡的研究,中國(guó)病理生理雜志, 2021, 37(7): 1210-1218。
3.彭鵬;張安琪;周曼莉;劉霏柳;張慧慧;張霞*; USP1通過(guò)調(diào)控E2F1對(duì)膀胱癌細(xì)胞增殖和周期的作用研究。中國(guó)細(xì)胞生物學(xué)學(xué)報(bào)。2022, 44(12): 2267–2275。
4.XIA ZHANG, XIAOLU ZHANG, LILI ZHUANG, CANGCANG XU, TAO LI, GUILI ZHANG and YING LIU. Decreased regulatory T.cell frequency and interleukin.35 levels in patients with rheumatoid arthritis. EXPERIMENTAL AND THERAPEUTIC MEDICINE 16: 5366-5372, 2018
5.Zhang, Xia,Liu, Riming,Huang, Baohua,Zhang, Xiaolu,Yu, Weijuan,Bao, Cuixia,Li, Jie,Sun, Chengming. Programmed cell death 4 and BCR-ABL fusion gene expression are negatively correlated in chronic myeloid leukemia,Oncology Letters,2016,12(4):2976~2981
6.Huang, Baohua,Chen, Lei,Bao, Cuixia,Sun, Chengming,Li, Jie,Wang, Lipeng,Zhang, Xia*. The expression status and prognostic significance of programmed cell death 1 ligand 1 in gastrointestinal tract cancer: a systematic review and meta-analysis.,OncoTargets and Therapy,2015,8:2617~2625
7.Zhang Xia,Wang, Xiaoyan,Song, Xingguo,Wei, Zengtao,Zhou, Chengjun,Zhu, Faliang,Wang, Qun,Ma, Chunhong,Zhang, Liling. Clinical and prognostic significance of lost or decreased PDCD5 expression in human epithelial ovarian carcinomas,ONCOLOGY REPORTS,2011,25(2):353~358
8.Zhang, Xia,Wang, Xiaoyan,Song, Xingguo,Liu, Chunmei,Shi, Yongyu,Wang, Yukun,Afonja, Olubunmi,Ma, Chunhong,Chen, Youhai H,Zhang, Lining. Programmed cell death 4 enhances chemosensitivity of ovarian cancer cells by activating death receptor pathway in vitro and in vivo,Cancer Science,2010,101(10):2163~2170
9.Song, Xingguo,Zhang, Xia,Wang, Xiaoyan,Zhu, Faliang,Guo, Chun,Wang, Qun,Shi, Yongyu,Wang, Jianing,Chen, Youhai,Zhang, Lining,Tumor expression of autophagy-related gene ATG5.,Autophagy,2013,9(5):743~755
10.Ding, Lingling,Zhang, Xia,Zhao, Miaoqing,Qu, Zhonghua,Huang, Shanying,Dong, Mei,Gao, Fei. An essential role of PDCD4 in progression and malignant proliferation of gastrointestinal stroma tumors. Med Oncol,2012,29(3):1758~1764
11.Li, Haiyan,Zhang, Xia, Song, Xingguo,Zhu, Faliang,Wang, Qun,Guo, Chun,Liu, Chunmei,Shi, Yongyu,Ma, Chunhong,Wang, Xiaoyan,Zhang, Lining. PDCD5 promotes cisplatin-induced apoptosis of glioma cells via activating mitochondrial apoptotic pathway,Cancer Biology and Therapy,2012,13(9):822~830