名字：劉真
照片：
職稱：講師
專業(yè)：藥學藥物化學
電子郵箱：liuzhen2020@hunnu.edu.cn
通訊地址：湖南省長沙市岳麓區(qū)桐梓坡路371號，bwin必贏至真樓303，郵編：410013
個人簡介：博士，碩士生導師。2008年畢業(yè)于北京大學，獲得藥學專業(yè)學士學位。2014年畢業(yè)于北京大學，獲得生藥學專業(yè)博士學位。之后在德國杜塞爾多夫大學藥物生物學與生物技術研究所進行博士后工作，從事微生物次生代謝產(chǎn)物的研究，2020年入職bwin必贏藥學系。長期從事新穎天然產(chǎn)物的發(fā)現(xiàn)和藥用研究，已從不同來源的動植物和微生物中分離并鑒定了800多個天然產(chǎn)物，其中新化合物300多個，以通訊作者或第一作者身份已發(fā)表SCI論文40多篇，擔任Journal of Natural Products，F(xiàn)rontiers in Microbiology，Bioorganic Chemistry等期刊審稿人。
近五年代表性學術論文：
1.Yu X, Gao Y, Frank M, Mándi A, Kurtán T, Müller WEG, Kalscheuer R, Guo Z, Zou K,Liu Z,*Proksch P.*Induction of ambuic acid derivatives by the endophytic fungusPestalotiopsis lespedezaethrough an OSMAC approach.Tetrahedron2021, 79, 131876.
2.Gao Y, Stuhldreier F, Schmitt L, Wesselborg S, Guo Z, Zou K, Mándi A, Kurtán T,Liu Z,*Proksch P.*Induction of new lactam derivatives from the endophytic fungusAplosporella javeediithrough an OSMAC approach.Frontiers in Microbiology2020, 11, 600983.
3.El-Kashef DH, Youssef FS, Hartmann R, Knedel TO, Janiak C, Lin W, Reimche I, Teusch N,Liu Z,*Proksch P.*Azaphilones from the Red Sea fungusAspergillus falconensis.Marine Drugs2020, 18, 204.
4.Pan F, El-Kashef DH, Kalscheuer R, Müller WEG, Lee J, Feldbrügge M, Mándi A, Kurtán T,Liu Z,*Wu W,*Proksch P.*Cladosins L-O, new hybrid polyketides from the endophytic fungusCladosporium sphaerospermumWBS017.European Journal of Medicinal Chemistry2020, 191, 112159.
5.Yu X, Müller WEG, Meier D, Kalscheuer R, Guo Z, Zou K, Umeokoli BO,Liu Z,*Proksch P.*Polyketide derivatives from mangrove derived endophytic fungusPseudopestalotiopsis theae.Marine Drugs2020, 18, 129.
6.Tran-Cong NM, Mándi A, Kurtán T, Müller WEG, Kalscheuer R, Lin W,Liu Z,*Proksch P.*Induction of cryptic metabolites of the endophytic fungusTrichocladiumsp. through OSMAC and co-cultivation.RSC Advances2019, 9, 27279-27288.
7.Frank M, Hartmann R, Plenker M, Mándi A, Kurtán T, ?zkaya FC, Müller WEG, Kassack MU, Hamacher A, Lin W,Liu Z,*Proksch P.*Brominated azaphilones from the sponge-associated fungusPenicillium canescensstrain 4.14.6a.Journal of Natural Products2019, 82, 2159-2166.
8.Liu S, Zhao Y, Heering C, Janiak C, Müller WEG, Akoné SH,Liu Z,*Proksch P.*Sesquiterpenoids from the endophytic fungusRhinocladiella similis.Journal of Natural Products2019, 82, 1055-1062.
9.Frank M, ?zkaya FC, Müller WEG, Hamacher A, Kassack MU, Lin W,Liu Z,*Proksch P.*Cryptic secondary metabolites from the sponge-associated fungusAspergillus ochraceus.Marine Drugs2019, 17, 99.
10.Yu H, Sperlich J, Mándi A, Kurtán T, Dai H, Teusch N, Guo ZY, Zou K,Liu Z,*Proksch P.*Azaphilone derivatives from the fungusConiella fragariaeinhibit NF-κB activation and reduce tumor cell migration.Journal of Natural Products2018, 81, 2493-2500.
11.Yu X, Zhang Q, Tian L, Guo Z, Liu C, Chen J, Ebrahim W,Liu Z,*Proksch P.*Zou K.*Germacrane-type sesquiterpenoids with antiproliferative activities fromEupatorium chinense.Journal of Natural Products2018, 81, 85-91.
12.Küppers L, Ebrahim W, El-Neketi M, ?zkaya FC, Mándi A, Kurtán T, Orfali RS, Müller WEG, Hartmann R, Lin W, Song W,Liu Z,*Proksch P.*Lactones from the sponge-derived fungusTalaromyces rugulosus.Marine Drugs2017, 15, 359.
13.Elnaggar MS, Ebrahim W, Mándi A, Kurtán T, Müller WEG, Kalscheuer R, Singab A, Lin WH,Liu Z,*Proksch P.*Hydroquinone derivatives from the marine-derived fungusGliomastixsp.RSC Advances2017, 7, 30640-30649.
14.Muharini R, Diaz A, Ebrahim W, Mándi A, Kurtán T, Rehberg N, Kalscheuer R, Hartmann R, Orfali RS, Lin W,Liu Z,*Proksch P.*Antibacterial and cytotoxic phenolic metabolites from the fruits ofAmorpha fruticosa.Journal of Natural Products2017, 80, 169-180.
15.Liu S, Dai H, Makhloufi G, Heering C, Janiak C, Hartmann R, Mándi A, Kurtán T, Müller WE, Kassack MU, Lin W,Liu Z,*Proksch P.*Cytotoxic 14-membered macrolides from a mangrove-derived endophytic fungus,Pestalotiopsis microspora.Journal of Natural Products2016, 79, 2332-2340.
16.Wang H, Dai HF, Heering C, Janiak C, Lin WH, Orfali RS, Müller WEG,Liu Z,*Proksch P.*Targeted solid phase fermentation of the soil dwelling fungusGymnascella dankaliensisyields new brominated tyrosine-derived alkaloids.RSC Advances2016, 6, 81685-81693.
17.Liu S, Dai H, Orfali RS, Lin W,Liu Z,*Proksch P.*New fusaric acid derivatives from the endophytic fungusFusarium oxysporumand their phytotoxicity to barley leaves.Journal of Agricultural and Food Chemistry2016, 64, 3127-3132.
