劉建軍個人簡歷
職稱:研究員
職務(wù):毒理研究所所長
專業(yè):公共衛(wèi)生與預(yù)防醫(yī)學(xué)
聯(lián)系電話:0755-25508584(Office)
電子郵箱:junii8@126.com
通訊地址:深圳市南山區(qū)龍?jiān)仿?號深圳市疾病預(yù)防控制中心,
郵編:518055
簡介:
劉建軍,女,研究員,正高二級技術(shù)崗位/博士生導(dǎo)師。廣東省醫(yī)學(xué)領(lǐng)軍人才、深圳市高層次領(lǐng)軍人才,享受國務(wù)院政府特殊津貼和深圳市政府特殊津貼。中國毒理學(xué)會和中國環(huán)境誘變劑學(xué)會理事,廣東省毒理學(xué)會和廣東省環(huán)境誘變劑學(xué)會副理事長,中華預(yù)防醫(yī)學(xué)會衛(wèi)生毒理分會常務(wù)委員,深圳市預(yù)防醫(yī)學(xué)會常務(wù)理事,深圳市預(yù)防醫(yī)學(xué)會毒理學(xué)評價專業(yè)委員會主任委員?,F(xiàn)任深圳市疾病預(yù)防控制中心毒理研究所所長和深圳市現(xiàn)代毒理學(xué)重點(diǎn)實(shí)驗(yàn)室學(xué)科帶頭人。主要研究方向?yàn)榛瘜W(xué)污染物致機(jī)體損傷的分子機(jī)制及生物標(biāo)志物研究、化學(xué)污染物暴露的健康風(fēng)險(xiǎn)評估研究、神經(jīng)退行性疾病的風(fēng)險(xiǎn)因素。在深圳市率先負(fù)責(zé)建立了蛋白質(zhì)組學(xué)研究技術(shù)平臺和開放實(shí)驗(yàn)室。先后主持國家自然科學(xué)基金4項(xiàng)、廣東省自然科學(xué)基金重點(diǎn)項(xiàng)目1項(xiàng)、廣東省自然科學(xué)基金2項(xiàng)、深圳市基礎(chǔ)研究學(xué)科布局項(xiàng)目2項(xiàng)、深圳市科技計(jì)劃重點(diǎn)項(xiàng)目2項(xiàng)、深圳市重點(diǎn)實(shí)驗(yàn)室提升發(fā)展項(xiàng)目2項(xiàng)、深圳市科技計(jì)劃項(xiàng)目4項(xiàng)。以第一完成人獲得國家、省級和市級科技成果獎6項(xiàng),分別為:廣東省科學(xué)技術(shù)獎二等獎1項(xiàng)和三等獎1項(xiàng)、中華醫(yī)學(xué)科技獎三等獎1項(xiàng)、中華預(yù)防醫(yī)學(xué)會科技獎二等獎1項(xiàng)、深圳市自然科學(xué)獎一等獎1項(xiàng)和深圳市科技創(chuàng)新獎1項(xiàng)。以主要完成人獲科技成果獎8項(xiàng),分別為廣東省自然科學(xué)獎二等獎1項(xiàng)、廣東省科技進(jìn)步獎二等獎1項(xiàng)、廣東省科學(xué)技術(shù)獎三等獎1項(xiàng)、深圳市科技進(jìn)步一等獎1項(xiàng)、深圳市科技進(jìn)步二等獎1項(xiàng)、深圳市科技創(chuàng)新獎3項(xiàng)。近年來以第一作者或通訊作者在Particle and Fibre Toxicology、Nanomedicine、Chemosphere、Toxicology and Applied Pharmacology、Toxicology Letters等國內(nèi)外知名期刊發(fā)表研究論文80多篇。主譯專著1部、參與編寫專著7部。獲國家發(fā)明專利授權(quán)5項(xiàng)(第一)。培養(yǎng)研究生35名和博士后5名。
社會(學(xué)術(shù))兼職:
1.中國毒理學(xué)會理事
2.中國環(huán)境誘變劑學(xué)會理事
3.中華預(yù)防醫(yī)學(xué)會衛(wèi)生毒理分會常務(wù)委員
4.廣東省毒理學(xué)會副理事長
5.廣東省環(huán)境誘變劑學(xué)會副理事長
6.深圳市預(yù)防醫(yī)學(xué)會常務(wù)理事
7.深圳市預(yù)防醫(yī)學(xué)會毒理學(xué)評價專業(yè)委員會主任委員
所獲獎勵:
1)典型職業(yè)與環(huán)境毒物健康損害關(guān)鍵分子鑒定、機(jī)制探索及應(yīng)用研究,中華預(yù)防醫(yī)學(xué)會科技獎二等獎,2019年,第一完成人.
2)干細(xì)胞皮膚再生研究,廣東省自然科學(xué)獎二等獎,2019年,第五完成人.
3)幾類化學(xué)污染物毒性機(jī)制、生物標(biāo)志物鑒別及應(yīng)用研究,中華醫(yī)學(xué)科技獎三等獎,2015年,第一完成人.
4)幾類化學(xué)污染物毒性關(guān)鍵分子鑒別與功能分析及應(yīng)用研究,廣東省科學(xué)技術(shù)獎二等獎,2014年,第一完成人.
5)代表性化學(xué)污染物毒性機(jī)制及應(yīng)用研究,深圳市自然科學(xué)獎一等獎,2013年,第一完成人.
6)蛋白質(zhì)組技術(shù)體系的建立及其在預(yù)防醫(yī)學(xué)中的應(yīng)用研究. 廣東省科學(xué)技術(shù)獎三等獎,2007年,第一完成人.
7)蛋白質(zhì)組技術(shù)體系的建立及其在預(yù)防醫(yī)學(xué)中的應(yīng)用研究. 深圳市科技創(chuàng)新獎,2007年,第一完成人.
8)Up-regulation of I2PP2A is Associated with Trichloroethylene-induced Cytotoxicity in L-02 Liver Cells.廣東省環(huán)境誘變劑學(xué)會2010年學(xué)術(shù)會議獲優(yōu)秀論文獎,2010年,通訊作者.
9)納米二氧化硅致HaCaT表皮細(xì)胞毒性作用的蛋白質(zhì)組學(xué)研究,中國環(huán)境誘變劑學(xué)會第十四屆學(xué)術(shù)交流會議青年優(yōu)秀論文一等獎,2009年,第一作者.
10)血清蛋白質(zhì)組分析方法篩選并鑒定TCE致L-02肝細(xì)胞損傷相關(guān)蛋白,第十屆中國科技年會“環(huán)境對遺傳毒性與腫瘤影響研討會”優(yōu)秀論文二等獎,2008年,第一作者.
11)帶His標(biāo)簽的癌蛋白SET真核表達(dá)載體的構(gòu)建. 第六屆中國毒理學(xué)會生化與分子毒理專業(yè)委員會全國學(xué)術(shù)會議優(yōu)秀論文,2008年,第一作者.
12)利用蛋白質(zhì)組學(xué)技術(shù)研究TCE刺激肝細(xì)胞后蛋白質(zhì)差異表達(dá). 深圳市科技學(xué)術(shù)年會優(yōu)秀論文獎,2005年,第一作者.
13)Identification of Serum Biomarkers for Occcupational Medicamentosa-like Dermatitics Induced by Trichloroethylene Using Mass Spectrometry.第13屆國際毒理學(xué)會議優(yōu)秀口頭報(bào)告二等獎,2013年,通訊作者.
14)Silica nanoparticles induce pathological signs of Alzheimer’s disease in rats.第六屆納米毒理學(xué)國際會議優(yōu)秀墻報(bào)獎,2012年,通訊作者.
15)基于阿爾茨海默病tau病理機(jī)制的環(huán)境風(fēng)險(xiǎn)因素、早期生物標(biāo)志物篩選及防治研究.深圳市科技進(jìn)步二等獎,2015年,第二完成人.
16)轉(zhuǎn)基因食品危險(xiǎn)性評估程序和方法的研究應(yīng)用,廣東省科技進(jìn)步獎三等獎,深圳市科技進(jìn)步獎,2013年,第五完成人.
17)低劑量環(huán)境化學(xué)物刺激細(xì)胞誘導(dǎo)損傷耐受的研究,廣西壯族自治區(qū)科學(xué)技術(shù)進(jìn)步獎三等獎,2010年,第四完成人.
18)幾種重要DNA修復(fù)基因?qū)瘜W(xué)物毒性的保護(hù)機(jī)制及多態(tài)性研究,廣東省科學(xué)技術(shù)獎二等獎和深圳市科技創(chuàng)新獎,2009年,第七完成人.
19)農(nóng)業(yè)轉(zhuǎn)基因生物食用安全性要求與評價標(biāo)準(zhǔn)體系研究,深圳市科技創(chuàng)新獎,2008年,第十完成人.
20)Hormesis and differential proteomic analysis in L-02 liver cells induced by low concentration trichoroethylene.中國蛋白質(zhì)組學(xué)第四屆學(xué)術(shù)大會優(yōu)秀論文,2006年,通訊作者.
21)人類SARS冠狀病毒溯源研究,深圳市科技進(jìn)步一等獎, 2004年,第十完成人.
主持的科研項(xiàng)目:
1)國家自然科學(xué)基金資助項(xiàng)目,NM23在長期低劑量三氯乙烯誘導(dǎo)自身免疫性肝炎中的作用及組蛋白修飾對其調(diào)控的機(jī)制(81872666),課題負(fù)責(zé)人,58萬元,2019-2022年.
2)國家自然科學(xué)基金資助項(xiàng)目,TCE作用下肝細(xì)胞中SET相關(guān)的表觀遺傳調(diào)控機(jī)制研究(81273126),課題負(fù)責(zé)人,60萬元,2013-2016年.
3)國家自然科學(xué)基金資助項(xiàng)目,SET在三氯乙烯肝細(xì)胞毒性中的作用及其機(jī)制研究(30972454),課題負(fù)責(zé)人,28萬元,2010-2012年.
4)國家自然科學(xué)基金資助項(xiàng)目,三氯乙烯職業(yè)中毒特異蛋白篩選及其蛋白質(zhì)相互作用研究(30571557),課題負(fù)責(zé)人,26萬元,2006-2008年.
5)廣東省自然科學(xué)基金重點(diǎn)項(xiàng)目,三氯乙烯致肝細(xì)胞毒性中SET相關(guān)的表觀遺傳調(diào)控機(jī)制研究(S2012020010903),課題負(fù)責(zé)人,30萬元,2013-2015年.
6)深圳市基礎(chǔ)研究學(xué)科布局項(xiàng)目,粵港澳灣區(qū)麻痹性貝類毒素(PSP)的監(jiān)控及其低劑量暴露致神經(jīng)退行性疾病的風(fēng)險(xiǎn)評估研究(JCYJ20180508152311822),課題負(fù)責(zé)人,200萬元,2019-2022年.
7)深圳市基礎(chǔ)研究學(xué)科布局項(xiàng)目,基于修飾蛋白質(zhì)組學(xué)的環(huán)境污染物鉻慢性致肺癌的關(guān)鍵分子標(biāo)志鑒定及機(jī)制研究(JCYJ20160428142316603),課題負(fù)責(zé)人,200萬元,2017-2019年.
8)深圳市“醫(yī)療衛(wèi)生三名工程”項(xiàng)目,神經(jīng)退行性疾病風(fēng)險(xiǎn)因素及預(yù)防研究(SZSM201611090),課題負(fù)責(zé)人,1000萬元,2017-2021年.
9)深圳市重點(diǎn)實(shí)驗(yàn)室提升發(fā)展項(xiàng)目,納米二氧化硅生物安全性及健康風(fēng)險(xiǎn)評價研究(ZDSY20120615085804889),課題負(fù)責(zé)人,80萬元,2013-2015年.
10)深圳市基礎(chǔ)研究計(jì)劃項(xiàng)目,貝類毒素?zé)晒饷嘎?lián)免疫檢測技術(shù)的研究(JCYJ20130329103949656),課題負(fù)責(zé)人,30萬元,2014-2015年.
11)深圳市基礎(chǔ)研究計(jì)劃項(xiàng)目,三氯乙烯致肝細(xì)胞毒性中SET功能相關(guān)蛋白的篩選與鑒定(JCYJ20120616154222545),課題負(fù)責(zé)人,10萬元,2013-2014年.
12)深圳市科技計(jì)劃重點(diǎn)項(xiàng)目,三氯乙烯致肝細(xì)胞毒性中SET相關(guān)的組蛋白修飾譜鑒別(201201027)課題負(fù)責(zé)人,10萬元,2013-2015年.
13)深圳市重點(diǎn)實(shí)驗(yàn)室提升發(fā)展項(xiàng)目,毒理蛋白質(zhì)組學(xué)技術(shù)平臺的建立及其在三氯乙烯致機(jī)體損傷機(jī)制研究中的應(yīng)用(CXB201005260068A),課題負(fù)責(zé)人,100萬元,2011-2014年.
14)深圳市科技計(jì)劃重點(diǎn)項(xiàng)目,蛋白磷酸酶2A抑制劑SET在三氯乙烯肝細(xì)胞毒性中的功能研究(200801010),課題負(fù)責(zé)人,10萬元,2009-2011年.
15)深港創(chuàng)新圈創(chuàng)新資源平臺:深港化學(xué)品安全性檢測技術(shù)平臺的建立,副主任,60萬元,2009-2011年.
16)廣東省自然科學(xué)基金資助項(xiàng)目(5009153),深圳市科技計(jì)劃項(xiàng)目(JH200505300493A),三氯乙烯職業(yè)中毒特異蛋白篩選及其蛋白質(zhì)相互作用研究,課題負(fù)責(zé)人,8萬元,2006-2008年.
17)廣東省自然科學(xué)基金資助項(xiàng)目,三氯乙烯職業(yè)中毒蛋白質(zhì)組差異表達(dá)研究(34970),課題負(fù)責(zé)人,5萬元,2004-2005年.
18)深圳市科技計(jì)劃項(xiàng)目,納米材料生物安全性評價方法研究(200702159),課題負(fù)責(zé)人,3萬元,2008-2009年.
代表性學(xué)術(shù)論文:
1.以第一作者或通訊作者發(fā)表的SCI論文(共35篇,*通訊作者)
1)Zhihong Chen,Jiacheng Zhong,Xiaohu Ren,Wei Liu,Desheng Wu,Chongyang Chen,Haiyan Huang,Xinfeng Huang,Yungang Liu,Jianjun Liu*.Involvement of a novel regulatory cascade consisting of SET-H3K18ac/H3K27ac-53BP1 in Cr(VI)-induced malignant transformation of 16HBE cells.Toxicol Lett, 2021, 339:70-77. [PMID: 33370592](IF=3.166)
2)Xiao Chen, Wei Liu, Lu Wang, Dafeng Lin, Lulin Nie, Kaiwu He, Zhiwei Guo, Feiqi Zhu, Wenting Feng, Weimin Liu, Jing Yuan, Xifei Yang, Peter Spencer,Jianjun Liu*.Diabetes mellitus is associated with elevated urinary pyrrole markers of γ-diketones known to cause axonal neuropathy.BMJ Open Diabetes Res Care,2020,8(1):e001575.[PMID:32912928] (IF=3.183).
3)Nuanyuan Luo, Qunqun Chang,·Xiaohu Ren, Peiwu Huang,Wei Liu, Li Zhou, Yungang Liu,Jianjun Liu*. Trichloroethylene injures rat liver and elevates the level of peroxisomal bifunctional enzyme (Ehhadh).Mol. Cell. Toxicol,2020,16:331-345.(IF=1.83).
4)Li Liu , Wei Liu , Lulin Nie , Zhiwei Guo , Yi Luo , Weihong Chen , Weimin Liu , Feiqi Zhu , Lu Wang , Jiafei Zhang , Xian Wang , Tian Li , Erwei Gao, Li Zhou , Kaiwu He , Yidan Huang , Chunjie Yuan , Qingqing Zhu , Fang Ye , Xingchen Yu , Jing Yuan ,Jianjun Liu*. Study Design and Baseline Characteristics of Shenzhen Ageing-Related Disorder Cohort in China.BMJ Open,2020,10(6): e034317. [PMID: 32565452] (IF=2.496).
5)Xian Wang , Jiafei Zhang , Li Zhou , Benhong Xu, Xiaohu Ren , Kaiwu He , Lulin Nie , Xiao Li ,Jianjun Liu*, Xifei Yang , Jing Yuan. Long-term Iron Exposure Causes Widespread Molecular Alterations Associated With Memory Impairment in Mice.Food Chem Toxicol, 2019,130: 242-252. [PMID: 31136779](IF=4.679).
6)Ren X, Xia B, Chen Z, Chen X, Wu D, Lu W, Luo N, Zhou L, Liu W, Yang X,Liu J*. Short-term and long-term exposure to hexavalent chromium alters 53BP1 via H3K18ac and H3K27ac.Chemosphere,2019,229: 284-294.[PMID:31078885] (IF=5.778).
7)Ren X, Chen Z, Ruan J, Zhong J, Deng R, Liu W, Huang X, Yang X, Liu Y,Liu J*. Trichloroethylene-induced downregulation of miR-199b-5p contributes to SET-mediated apoptosis in hepatocytes.Cell Biol Toxicol,2019, 35(6): 565-572. [PMID:31140026] (IF=6.284).
8)Zhong J, Ren X, Chen Z, Zhang H, Zhou L, Yuan J, Li P, Chen X, Liu W, Wu D, Yang X,Liu J*. miR-21-5p promotes lung adenocarcinoma progression partially through targeting SET/TAF-Iα.Life Sci,2019, 231:116539. [PMID:31176779] (IF=3.647).
9)Lu W, Chen Z, Ren X, Liu W, Deng R, Yuan J, Huang X, Zhu W,Liu J*.SET promotes H2Ak9 acetylation by suppressing HDAC1 in trichloroethylene-induced hepatic cytotoxicity.Environ Toxicol Pharmacol,2018, 59:125-131. [PMID:29579541] (IF=3.292).
10)Chen X, Sun Y, Huang H, Liu W, Hu P, Huang X, Zou F,Liu J*. Uncovering the proteome response of murine neuroblastoma cells against low-dose exposure to saxitoxin.Toxicol Mech Methods, 2018, 28(5): 335-344.[PMID: 29228856] (IF=1.994).
11)Liu W, Hu T, Zhou L, Wu D, Huang X, Ren X, Lv Y, Hong W, Huang G, Lin Z,Liu J*.Nrf2 protects against oxidative stress induced by SiO2 nanoparticles.Nanomedicine (Lond), 2017, 12(19): 2303-2318.[PMID: 28952419](IF=5.005).
12)Ren X,Huang X,Yang X,Liu Y,Liu W,Huang H,Wu D,Zou F,Liu J*.SET mediates TCE-induced liver cell apoptosis through dephosphorylation and upregulation of nucleolin.Oncotarget,2017,8(25):40958-40966.[PMID: 28402964](IF=5.168).
13)Hong WX, Huang A, Lin S, Yang X, Yang L, Zhou L, Huang H, Wu D, Huang X, Xu H,Liu J*.Differential expression profile of membrane proteins in L-02 cells exposed to trichloroethylene.Toxicol Ind Health,2016,32(10):1774-1783.[PMID: 26045551] (IF=1.255).
14)Liu W,Hong WX,Zhang YW,Ren XH,Li PM, Zhang ZM,Huang HY,Huang XF, Zhang YF,Liu JJ*.Dynamic Change of Serum Proteomics of Occupational Medicamentosa-like Dermatitis Induced by Trichloroethylene.IntJ Clin Exp Pathol, 2016, 9(7): 7381-7392.[PMID: 24631019](IF=1.396).
15)Xia B, Pang L, Zhuang ZX,Liu JJ*. Biotin-mediated epigenetic modifications: Potential defense against the carcinogenicity of benzo[a]pyrene.Toxicol Lett, 2015, 241(2):216-224. [PMID: 26569572] (IF=3.166).
16)Ren X, Li J, Xia B, Liu W, Yang X, Hong WX, Huang P, Wang Y, Li S, Zou F,Liu J*.Phosphoproteomic analyses of L-02 liver cells exposed to trichloroethylene.Toxicol Mech Methods, 2015, 25(6):459-466. [PMID: 26018768] (IF=1.994).
17)Liu J, Huang P, He Y, Hong WX, Ren X, Yang X, He Y, Wang W, Zhang R, Yang H, Zhao Z, Huang H, Chen L, Zhao D, Xian H, Yang F, Ma D, Yang L, Yin Y, Zhou L, Chen X, Cheng J. Serum amyloid A and clusterin as potential predictive biomarkers for severe hand, foot and mouth disease by 2D-DIGE proteomics analysis.PLoS One, 2014,9(9):e108816. [PMID:25268271] (IF=2.806).
18)Ren X, Yang X, Hong W, Huang P,Wang Y, Liu W, Ye J, Huang H, Huang X, Shen L, Yang L, Zhuang Z,Liu J*. Identification of the proteins related to SET-mediated hepatic cytotoxicity of trichloroethylene by proteomic analysis.Toxicol Lett, 2014, 227(1):12-19. [PMID: 24631019] (IF=3.166).
19)Zhang H, Hong WX, Ye J, Yang X, Ren X, Huang A, Yang L, Zhou L, Huang H, Wu D, Huang X, Zhuang Z,Liu J*. Analysis of trichloroethylene-induced global DNA hypomethylation in hepatic L-02 cells by liquid chromatography-electrospray ionization tandem mass spectrometry.Biochem Biophys Res Commun,2014, 446(2):590-595.[PMID:24632203] (IF=2.466).
20)Huang P,Ren X,Huang Z,Yang X,Hong W,Zhang Y,Zhang H,Liu W,Huang H,Huang X,Wu D,Yang L,Tang H,Zhou L,Li X,Liu J*. Serum proteomic analysis reveals potential serum biomarkers for occupational medicamentosa-like dermatitis caused by trichloroethylene.Toxicol Lett,2014,229 (1):101-110. [PMID: 24960064] (IF= 3.166) .
21)Liu W, Hong WX, Zhang Y, Huang P, Yang X, Ren X, Huang H,Liu J*. Proteomic profiling of occupational medicamentosa-like dermatitis induced by trichloroethylene in serum based on MALDI-TOF MS.Clin Exp Med,2015, 15(4): 519-526. [PMID:25475505] (IF=2.919).
22)Yang X, He C, Li J, Chen H,Ma Q, Sui X, Tian S,Ying M, Zhang Q,Luo Y, Zhuang Z,Liu J*. Uptake of Silica Nanoparticles: Neurotoxicity and Alzheimer-like Pathology in Human SK-N-SH and Mouse Neuro2a Neuroblastoma Cells.Toxicol Lett, 2014,229(1):240-249. [PMID:24831964](IF=3.166) .
23)Sui X, Ren X, Huang P, Li S, Ma Q, Ying M, Ni J,Liu J*, Yang X. Proteomic analysis of serum proteins in triple transgenic Alzheimer's disease mice: implications for identifying biomarkers for use to screen potential candidate therapeutic drugs for early Alzheimer's disease.J Alzheimers Dis,2014,40(3):575-586. [PMID:24496070] (IF=3.731).
24)Xia B, Ren XH, Zhuang ZX, Yang LQ, Huang HY, Pang L, Wu DS, Luo J, Tan YL,Liu JJ*,Zou F. Effect of hexavalent chromium on histone biotinylation in human bronchial epithelial cells.Toxicol Lett,2014 ,228(3):241-247.[PMID: 24858232] (IF=3.166).
25)Li J, Yang XF, Ren XH, Meng XJ, Huang HY, Zhao QH, Yuan JH, Hong WX, Xia B, Huang XF, Zhou L,Liu JJ*, Zou F. Stable SET knockdown in breast cell carcinoma inhibits cell migration and invasion.Biochem Biophys Res Commun.2014,453(1):7-12. [PMID:25234598] (IF=2.466).
26)Hong WX, Liu W, Zhang Y, Huang P, Yang X, Ren X, Ye J, Huang H, Tang H, Zhou G, Huang X, Zhuang Z,Liu J*.Identification of serum biomarkers for occupational medicamentosa-like dermatitis induced by trichloroethylene using mass spectrometry.Toxicol Appl Pharmacol. 2013,273(1): 121‐129.[PMID: 23994554] (IF=3.616).
27)Yang X,Shen Z,Zhang B,Yang J,Hong WX,Zhuang Z,Liu J*.Silica Nanoparticles Capture AtmosphericLead: Implications in theTreatment of Environmental Heavy Metal Pollution.Chemosphere, 2013, 90(2):653-656.[PMID: 23084516](IF=4.427).
28)Huang H, Huang A, Zhuang Z, Huang W, Fu Y, Peng C,Liu J*.Study of cytoskeletal changes induced by okadaic acid in HL-7702 liver cells and development of a fluorimetric microplate assay for detecting diarrhetic shellfish poisoning.Environ Toxicol,2013, 28(2):98-106. [PMID: 21544917] (IF=2.491).
29)Hong WX,Ye JB,Chen MT,Yan Y,Zhou GF,Yang XF,Yang L,Ren XH,Huang HY,Zhou L,Huang XF,Zhuang ZX,Liu JJ*.Trichloroethylene Induces Biphasic Concentration-dependent Changes in Cell Proliferation and the Expression of SET-Associated Proteins in Human Hepatic L-02 Cells.Biomed Environ Sci,2013; 26(7): 618‐621.[PMID: 23895710](IF=2.518).
30)Hong WX, Yang L, Chen M, Yang X, Ren X, Fang S, Ye J, Huang H, Zhou L, Huang X, Yang F, WuD, Zhuang Z,Liu J*.Proteomic analysis of trichloroethylene-induced alterations in expression, distribution, and interactions of SET/TAF-Iα and SET/TAF-Iα-binding proteins, eEF1A1 and eEF1A2 in hepatic L-02 cells.Toxicol Appl Pharmacol, 2012, 263(2):259-272 [PMID:22771849] (IF=3.616).
31)Yang X, Jiang Y, Li J, Hong WX, Wu D, Huang X, Huang H, Zhou L, Yang L, Yuan J, Zhuang Z,Liu J*. Lentivirus-mediated silencing of I2PP2A through RNA interference attenuates trichloroethylene-induced cytotoxicity in human hepatic L-02 cells.Toxicol Lett, 2012, 209(3):232-238. [PMID: 22245669] (IF=3.166).
32)Yang X,Liu J*, He H, Zhou L, Gong C, Wang X, Yang L, Yuan J,Huang H, He L, Zhang B, Zhuang Z. SiO2 nanoparticles induce cytotoxicity and protein expression alteration in HaCaT Cells.Part Fibre Toxicol, 2010, 7(1):1. [PMID: 20180970] (IF=6.105).
33)Huang HY,Liu JJ(共同第一作者), Xi RR, Xing XM, Yuan JH, Yang LQ, Tao GH, Gong CM, Zhuang ZX.An investigation of hormesis of trichloroethylene in L-02 Liver cells by differential proteomic analysis.Mol Biol Rep, 2009, 36: 2119–2129.[PMID: 19109764] (IF=1.889).
34)Liu J, Xing X, Huang H, Jiang Y, He H, Xu X, Yuan J, Zhou L, Yang L, Zhuang Z. Identification of antigenic proteins associated with trichloroethylene-induced autoimmune disease by serological proteome analysis.Toxicol Appl Pharmacol, 2009, 240(3):393-400. [PMID: 19647757] (IF=3.616).
35)Liu J, Huang H, Xing X, Xi R, Zhuang Z, Yuan J, Yang F, Zhao J.Compartive proteomic analysis on human L-02 liver cells treated with varying concentrations of trichloroethylene.Toxicol Ind Health, 2007, 23(2): 91-101. [PMID: 18203561] (IF=1.255).
2.以第一作者或通訊作者發(fā)表的主要中文論文(共23篇,*通訊作者 )
1)黃超, 劉威, 呂媛, 劉建軍*.阿爾茨海默病流行現(xiàn)狀及非藥物干預(yù)研究進(jìn)展. 中華老年醫(yī)學(xué)雜志, 2020, 39(1): 100-104.
2)王舒奇, 劉威, 呂媛, 任曉虎, 聶露琳, 何開武, 陳志鴻, 羅暖媛,劉建軍*.深圳市某區(qū)老年人輕度認(rèn)知功能障礙影響因素的病例對照研究. 華南預(yù)防醫(yī)學(xué), 2019, 45(3): 268-271.
3)陳志鴻, 羅暖媛, 任曉虎, 王舒奇, 黃超, 劉云崗, 劉建軍*. 基于定量蛋白質(zhì)組學(xué)技術(shù)的鉻致細(xì)胞惡化轉(zhuǎn)化中SET的潛在作用分析. 中華勞動衛(wèi)生職業(yè)病雜志, 2019, 37(3): 169-173.
4)任曉虎, 盧維雪, 陳志鴻, 劉威, 王舒奇, 羅暖媛, 劉建軍*. 六價鉻致16HBE細(xì)胞DNA損傷相關(guān)惡性轉(zhuǎn)化的研究. 中華勞動衛(wèi)生職業(yè)病雜志, 2018, 36(7): 481-484.
5)阮嘉雯, 陳志鴻, 盧維雪, 張航, 任曉虎, 黃新鳳, 袁建輝, 劉云崗, 劉建軍*. 三氯乙烯致肝細(xì)胞毒性中SET啟動子區(qū)甲基化水平的改變. 中華勞動衛(wèi)生職業(yè)病雜志, 2018, 36(3): 165-168.
6)陳志鴻, 盧維雪, 夏菠, 劉建軍*.六價鉻化合物致肺癌的研究進(jìn)展.中華勞動衛(wèi)生職業(yè)病雜志, 2017, 35(11): 875-878.
7)鄧榮霞, 任曉虎, 阮嘉雯, 鄭劍, 鐘佳成, 盧維雪, 鄒曉青, 劉建軍*. 三氯乙烯對人正常肝細(xì)胞組蛋白質(zhì)甲基化修飾影響的研究.中華預(yù)防醫(yī)學(xué)雜志, 2017, 51(4): 347-352.
8)劉建軍. 加強(qiáng)預(yù)防三氯乙烯的職業(yè)健康危害.中華預(yù)防醫(yī)學(xué)雜志, 2015,49(3):193-195.
9)黃培武, 李絢, 劉威, 劉建軍*. 三氯乙烯非致癌性毒性研究進(jìn)展.中華預(yù)防醫(yī)學(xué)雜志, 2015, 49(9): 97-101.
10)黃培武, 李絢, 任曉虎, 劉建軍*. 三氯乙烯及其代謝物致癌性研究進(jìn)展.中華預(yù)防醫(yī)學(xué)雜志, 2015, 49(3): 284-288.
11)洪文旭, 黃愛博, 許華, 張航, 葉金波, 劉建軍*. SET基因缺陷對三氯乙烯誘導(dǎo)人正常肝細(xì)胞DNA甲基化水平改變的影響.中華預(yù)防醫(yī)學(xué)雜志,2015, 49(3): 206-211.
12)黃愛博, 許華, 洪文旭, 莊志雄, 劉建軍*. 三氯乙烯對人正常肝細(xì)胞亞細(xì)胞蛋白質(zhì)組影響的研究.中華預(yù)防醫(yī)學(xué)雜志,2015, 49(3): 212-217.
13)張航, 劉威, 劉建軍*. microRNA的功能及其臨床應(yīng)用.生物技術(shù)通訊, 2015, 26(2): 278-282.
14)張航, 胡俊杰, 葉金波, 任曉虎, 劉建軍*.高效液相色譜-串聯(lián)質(zhì)譜檢測基因組DNA甲基化方法的建立.生物技術(shù)通訊. 2014, 25(4):537-541.
15)胡韜, 申治國, 孫燁, 周麗, 劉建軍*.納米二氧化硅對車間空氣中鎘的吸附效應(yīng).環(huán)境與健康雜志, 2014, 31(11): 1023-1024.
16)黃培武, 任曉虎, 洪文旭, 楊細(xì)飛, 張航, 李杰, 張艷芳, 劉建軍*.一例三氯乙烯藥疹樣皮炎患者不同發(fā)病時期血清蛋白質(zhì)組分析.中華預(yù)防醫(yī)學(xué)雜志, 2014, 48(5): 420-430.
17)葉金波, 劉威, 周桂鳳, 任曉虎, 黃培武, 洪文旭, 黃海燕, 劉建軍*. 職業(yè)性三氯乙烯藥疹樣皮炎診斷模型的建立.中華預(yù)防醫(yī)學(xué)雜志, 2013, 47(2):151-154.
18)劉建軍, 蔣英芝, 葉金波, 李杰, 楊細(xì)飛, 周麗, 黃海燕, 黃新鳳. SET基因shRNA慢病毒載體的構(gòu)建及其在肝細(xì)胞中的表達(dá)鑒定.癌變?畸變?突變,2013, 25(1):44-52.
19)劉威, 劉建軍*.基質(zhì)輔助激光解吸電離飛行時間質(zhì)譜技術(shù)篩選人血清蛋白標(biāo)志的研究進(jìn)展.衛(wèi)生研究, 2012, 41(3): 526-530.
20)劉威, 張艷芳, 張志敏, 李培茂, 姜曉東, 周桂鳳, 劉建軍*.三氯乙烯藥疹樣皮炎患者肝功能損害動態(tài)變化.中華勞動衛(wèi)生職業(yè)病雜志, 2011, 29(10): 790-794.
21)劉建軍,邢秀梅, 黃海燕, 袁建輝, 徐新云, 周麗, 楊細(xì)飛, 方道奎. 三氯乙烯藥疹樣皮炎差異血清蛋白的篩選及鑒定.中華預(yù)防醫(yī)學(xué)雜志,2010,44(6): 485-489.
22)任曉虎, 劉建軍*.磷酸化蛋白質(zhì)組學(xué)技術(shù)進(jìn)展及其在預(yù)防醫(yī)學(xué)中的應(yīng)用.中華預(yù)防醫(yī)學(xué)雜志,2010,44(6): 542-545.
23)劉建軍, 莊志雄. 毒理蛋白質(zhì)組學(xué)與人類健康危險(xiǎn)度評價.中華預(yù)防醫(yī)學(xué)雜志, 2010, 44(6): 478-479.
3.以合作作者發(fā)表的主要SCI論文
1)Chao Zhao, Peisi Xie, Ting Yong, Wei Huang, Jianjun Liu, Desheng Wu, Fenfen Ji, Min Li, Doudou Zhang, Ruijin Li, Chuan Dong, Juan Ma, Zheng Dong, Sijin Liu, Zongwei Cai Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy.Sci Bull, doi.org/10.1016/j.scib.2020.08.036. (IF=9.511)
2)Zihuan Li, Hang Yu, Meiqi Song, Hansruedi Glatt, Jianjun Liu, Yungang Liu.Potent aneugenicity of 1-methylpyrene in human cells dependent on metabolic activation by endogenous enzymes.Arch Toxicol, 2021,95(2):703-713. [PMID:33057863] (IF=5.059)
3)Yang X, Zhang Y, Xu H, Luo X, Yu J,Liu J, Chang RC. Neuroprotection of Coenzyme Q10 in Neurodegenerative Diseases.Curr Top Med Chem, 2016, 16(8), 858-866. [PMID:26311425] (IF=2.90)
4)Yu J, Luo X, Xu H, Ma Q, Yuan J, Li X, Chang RC, Qu Z, Huang X, Zhuang Z,Liu J, Yang X. Identification of the key molecules involved in chronic copper exposure-aggravated memory impairment in transgenic mice of Alzheimer's disease using proteomic analysis.J Alzheimers Dis,2015, 44(2):455-469. [PMID:25352456] (IF=4.151).
5)Ma Q, Ying M, Sui X, Zhang H, Huang H, Yang L, Huang X, Zhuang Z,Liu J, Yang X. Chronic copper exposure causes spatial memory impairment, selective loss of hippocampal synaptic proteins, and activation of PKR/eIF2α pathway in mice.J Alzheimers Dis,2015, 43(4):1413-1427. [PMID:25159668] (IF=4.151).
6)Liu JD,Liu JJ,Yuan JH,Tao GH,Wu DS,Yang XF,Yang LQ,Huang HY,Zhou L,Xu XY,Hu JJ,Zhuang ZX.Proteome of melamine urinary bladder stones and implication for stone formation.Toxicol Lett,2012, 212(3):307-314. [PMID: 22688180] (IF=3.262).
7)Wu D,Liu J, Zhao Q, Xu X, Yang L, Huang H, Yuan J, Zhou L, Zhuang Z. Characterization of the disposition of melamine in female Sprague-Dawley rats using ultra-performance liquid chromatography-tandem mass spectrometry.J Anal Toxicol,2011, 35(8):551-557. [PMID: 22004674] (IF=2.858).
8)Yang X, Yang Y,Liu J,Li G, Yang E.Increased Phosphorylation of Tau and Synaptic Protein Loss in the Aged Transgenic Mice Expressing Familiar Alzheimer's Disease-Linked Presenilin 1 Mutation.Neurochem Res.2012, 37(1):15-22. [PMID: 21842270]. (IF= 2.593).
9)Gong C, Tao G, Yang L,Liu J, Liu Q, Li W, Zhuang Z. Methylation of PARP-1 promoter involved in the regulation of nano-SiO(2)-induced decrease of PARP-1 mRNA expression.Toxicol Lett,2012, 209(3):264-269. [PMID: 22265868] (IF=3.262).
10)Gong C, Tao G, Yang L,Liu J, Liu Q, Zhuang Z. SiO(2) nanoparticles induce global genomic hypomethylation in HaCaT cells.Biochem Biophys Res Commun,2010, 397(3):397-400. [PMID: 20501321] (IF=2.297).
11)Gong C, Tao G, Yang L,Liu J, He H, Zhuang Z. The role of reactive oxygen species in silicon dioxide nanoparticle-induced cytotoxicity and DNA damage in HaCaT cells.Mol Biol Rep,2012,39(4): 4915-4925. [PMID: 22179747] (IF=2.024).
12)Luo Y, Liu X, Zheng Q, Wan X, Ouyang S, Yin Y, Sui X,Liu J, Yang X. Hydrogen sulfide prevents hypoxia-induced apoptosis via inhibition of an H2O2-activated calcium signaling pathway in mouse hippocampal neurons.Biochem Biophys Res Commun. 2012; 425(2):473-477. [PMID: 22846576](IF=2.297).
13)Liu Q, Yang L, Gong C, Tao G, Huang H,Liu J, Zhang H, Wu D, Xia B, Hu G, Wang K, Zhuang Z. Effects of long-term low-dose formaldehyde exposure on global genomic hypomethylation in 16HBE cells.Toxicol Lett,2011, 205(3):235-240. [PMID: 21745553] (IF=3.262).
14)Xia B, Yang LQ, Huang HY, Pang L, Hu GH, Liu QC, Yuan JH,Liu JJ, Xia YB, Zhuang ZX. Chromium (VI) causes down regulation of biotinidase in human bronchial epithelial cells by modifications of histone acetylation.Toxicol Lett,2011, 205(2):140-145. [PMID: 21641978] (IF=3.262).
15)Yang L,Luo L,Ji W,Gong C,Wu D,Huang H,Liu Q,Xia B,Hu G,Zhang W,Zhang Q,Liu J,Zhang W,Zhuang Z. Effect of low dose bisphenol A on the early differentiation of human embryonic stem cells into mammary epithelial cells.Toxicol Lett,2013, 218(3):187-193. [PMID: 23391485](IF=3.262).
16)Tao GH, Yang LQ, Gong CM, Huang HY, Liu JD,Liu JJ, Yuan JH, Chen W, Zhuang Z.Effect of PARP-1 deficiency on DNA damage and repair in human bronchial epithelial cells exposed to Benzo(a)pyrene.Mol Biol Rep,2009,36(8):2413-2422. [PMID: 19247804] (IF=2.024).
17)Huang HY, Cai JF, Liu QC, Hu GH, Xia B, Mao JY, Wu DS,Liu JJ,Zhuang ZX.Role of poly(ADP-ribose) glycohydrolase in the regulation of cell fate in response to benzo(a)pyrene.Exp Cell Res. 2012, 318(5):682-690. [PMID: 22266578] (IF=3.246).
18)Huang H, Li X,Hu G,Li X, Zhuang Z,Liu J, Wu D, Yang L, Xu X, Huang X, Zhang J, Hong WX, Yuan J, Gao W, Liu Y.Poly(ADP-ribose) glycohydrolase silencing down-regulates TCTP and Cofilin-1 associated with metastasis inbenzo(a)pyrene carcinogenesis.Am J Cancer Res. 2014,5(1):155-167.[PMID:25628927] (IF=4.165).
19)Sui X,Liu J, Yang X. Cerebrospinal fluid biomarkers of Alzheimer’s diseaseNeurosci Bull. 2014,30(2): 233-242. [PMID:24733653] (IF=2.509).
20)Huang H, Hu G, Cai J, Xia B,Liu J, Li X, Gao W, Zhang J, Liu Y, Zhuang Z. Role of poly(ADP-ribose) glycohydrolase silencing in DNA hypomethylation induced by benzo(a)pyrene.Biochem Biophys Res Commun.2014,452(3):708-714. [PMID:25195819] (IF=2.297).
授權(quán)專利:
1)劉建軍,任曉虎,阮嘉雯,劉威,黃新鳳. 一種肝細(xì)胞miR-199b低表達(dá)的慢病毒表達(dá)載體及其構(gòu)建方法,2019年獲得國家發(fā)明專利授權(quán)證書,專利號:ZL 2018 1 0362418.5.
2)任曉虎,劉建軍,黃新鳳,鐘佳成,阮嘉雯. 促進(jìn)肝細(xì)胞miR-199b高表達(dá)的慢病毒表達(dá)載體及其構(gòu)建方法,2019年獲得國家發(fā)明專利授權(quán)證書,專利號:ZL 2016 1 0325842.3.
3)劉建軍,黃海燕,孫燁,劉威,任曉虎,彭朝瓊,黃新鳳. 一種基于а烯醇化酶的麻痹性貝類毒素細(xì)胞檢測法,2017年獲得國家發(fā)明專利授權(quán)證書,專利號:ZL 2016 1 02311544.0.
4)劉建軍,黃海燕,黃愛君,黃薇,莊志雄,彭朝瓊,袁建輝. 腹瀉性貝類毒素檢測方法,2012年獲得國家發(fā)明專利授權(quán)證書,專利號:ZL 2010 1 0266834.9.
5)劉建軍,席仁榮,黃海燕,邢秀梅,彭朝瓊,周麗. SET基因RNA干擾重組載體及其構(gòu)建方法和應(yīng)用,2013年獲得國家發(fā)明專利授權(quán)證書,專利號: ZL2010 1 0255674.8.
6)劉建軍,蔣英芝,楊細(xì)飛,李杰,周麗. 特異性抑制SET蛋白表達(dá)的shRNA表達(dá)載體及其構(gòu)建方法和應(yīng)用,2013年獲得國家發(fā)明專利授權(quán)證書,專利號:ZL2010 1 0255722.3.
專著編寫:
1)《現(xiàn)代毒理學(xué)》,編著者,人民衛(wèi)生出版社,2018年.
2)《分子毒理學(xué)》,編委,人民衛(wèi)生出版社,2016年.
3)《納米毒理學(xué)》,主譯,科學(xué)出版社,2009年.
4)《自由基生物醫(yī)學(xué)》,編著者,臺灣藝軒出版社,2013年.
5)《自由基毒理學(xué)》,編著者,人民衛(wèi)生出版社,2012年.
6)《深圳市疾病預(yù)防控制中心工作規(guī)范》,編委,人民衛(wèi)生出版社,2009年.
7)《農(nóng)業(yè)轉(zhuǎn)基因生物食用安全性要求與評價》, 編著者,人民衛(wèi)生出版社,2008年.
8)《轉(zhuǎn)基因食品食用安全性和營養(yǎng)質(zhì)量評價及驗(yàn)證》,編著者,人民衛(wèi)生出版社,2003年.
發(fā)表的國際會議口頭報(bào)告或摘要,*通訊作者:
1)Xiaohu Ren,Jianjun Liu*,et al. SET-mediated Suppression of Histone H3k18ac and H3k27ac Promotes Hexavalent Chromium Induced Malignant Transformation Partially Through Down-regulation of 53BP1.13th Biennial Conference,ISTERH2019, Sep. 22-26, 2019,Bali Island,Indonesia.(口頭報(bào)告)
2)Jianjun Liu.Down-regulation of p53 by SET contributes to TCE-induced DNA damage through inhibition of H3K79 di-methylation. 2018 International Conference on Mass Spectrometry and Proteomics, June 25-27, 2018, Dublin, Ireland. (分會主席, 口頭報(bào)告)
3)Jianjun Liu.Proteomic study of SET-mediated abnormal protein phosphorylation and histone modification in trichloroethylene-induced hepatic cytotoxicty.2nd International Conference on Current Trends in Mass Spectrometry, July 20-22, 2016, Chicago, USA. (分會主席, 口頭報(bào)告)
4)劉建軍,作為“The XIII International Congress of Toxicology(ICT 2013) in conjunction with The 2nd(2013) International Conference on Environmental OMICS (ISEO)”組織委員會委員,組織了一個專題分會,并擔(dān)任專題分會主席: Chair for session E02:Molecular and Cellular Toxicity Mechanisms and Adverse Health Outcomes. July 1, 2013, Seoul, Korea, E02, P25.(分會主席)
5)劉建軍,作為“2011 International Conference on Environmental OMICS (ISEO)”1個主旨報(bào)告會主席,1個分會報(bào)告主席:Co-Chairfor keynote and plenarySession Ⅲin Nov. 10, 2011 and as Chair for Session D4: Predictiveproteomics: toxicity pathways, signatures, and adverse health outcomes in Nov. 9,2011, Guangzhou, China, P28-29.(分會主席)
6)Jianjun Liu, Xiaohu Ren, Bo Xia,et al. Studies of SET-mediated protein phosphorylation and nucleolin self-regulatory in trichloroethylene-induced hepatic cytotoxicity.The Gordon Research Conference on Posttranslational Modification Networks,July 5-10, 2015, Hongkong. (口頭報(bào)告)
7)Jianjun Liu, Xiaohu Ren, Bo Xia,et al. Proteomic study of SET-mediated phosphorylation and regulatory analysis of nucleolin in trichloroethylene-induced hepatic cytotoxicity.Proteomic Forum 2015,March 22-25,2015, Berlin, GermanyPoster P163.
8)Jianjun Liu. Proteomics study of SET-mediated hepatic cytotoxicity induced by TCE. The 4thAsian Conference Environmental Mutagens, Dec. 10-12, 2014, Kolkata, India. Omics in toxicology.(口頭報(bào)告)
9)Liu JJ, Ren XH, Yang XF,et al.Identification of the Proteins Related to SET-mediated Hepatic Cytotoxicity of Trichloroethylene by Proteomic Analysis. The US Environmental Mutagenesis and Genomics Society 44th Annual Meeting, Sep. 21-25, 2013, Monterey, US, Poster LB4.
10)Wen-Xu Hong, Wei Liu,Jianjun Liu*. Identification of Serum Biomarkers for Occcupational Medicamentosa-like Dermatitics Induced by Trichloroethylene Using Mass Spectrometry. The XIII International Congress of Toxicology(ICT 2013), Jun30-Jul 4, 2013, Seoul, Korea, E04, P29. (口頭報(bào)告)
11)Jianjun Liu, Xifei Yang, Chun’e He,et al. Silica Nanoparticles Induce Neurotoxicity and Alzheimer-like Pathological Signs in Neurblastoma Cells.Conference paper, The 6th International Confernece on Nanotoxicology,2012.
12)Hong Wen-Xu , Chen Moutong ,Liu Jianjun*,et al.Altered interaction between eEF1A1s and SET in trichloroethylene-treated human L-02 liver cells.The 7th Chinese Proteomics Conference & 3rd Interantional Proteomics Forum, 2011, P27.(口頭報(bào)告)
13)Hong Wen-Xu , Chen Moutong ,Liu Jianjun*,et al.Altered interactions between eEF1As and SET in trichloroethylene-treated human L-02 liver cells. 2011 International Conference on Environmental OMICS (ISEO),2011,P28.(口頭報(bào)告)
14)Xifei Yang, Yingzhi Jiang,Jianjun Liu*,et al. Lentivirus-mediated RNA interference targeting I2PP2A attenuated trichloroethylene-induced cytotoxicity in human L-02 Liver cells. 2011 International Conference on Environmental OMICS (ISEO), 2011,P25.(口頭報(bào)告)
15)Jianjun Liu, Moutong Chen, Xifei Yang,et al.Identification of the novel interaction proteins of SET in L-02 liver cells treated with trichloroethylene.XII International Congress of Toxicology(Barcelona-Spain 19-23 July 2010), P42, (P104-018).
16)劉建軍,黃海燕,黃愛君,等.大田軟海綿酸的熒光檢測法研究.第九屆粵港澳臺預(yù)防醫(yī)學(xué)學(xué)術(shù)會議,Nov. 6-7, 2010, Hongkong,Poster,P115.
17)Xifei Yang,Jianjun Liu*, Haowei He,et al. Nanometer SiO2induces toxicological effects and protein expression alterationin HaCaT cells. 2009 Wuhan International Conference on the Environment (WICE), 2009. (口頭報(bào)告)
18)Jianjun Liu, Xiumei Xing, Zhixiong Zhuang,et al. Identification of trichloroethylene intoxication associated liver cell proteins by serological proteome analysis. The 5th Society of Environmental Toxicology and Chemistry (SETAC) World Congress,Sydney, Australia, Poster 24, Omics, 2008, Aug, Program Book, P134.
19)Jianjun Liu, Haiyan Huang , Xiumei Xing ,et al. Comparative proteomic analysis on human L-02 liver cells treated with varying concentrations of trichloroethylene. XI International Congress of Toxicology, Montreal, Canada, 2007, Jul, Poster PT3.060(058).
20)Jianjun Liu, Haiyan Huang , Zhixiong Zhuang,et al. Differential proteomic analysis on the cellular responses in human liver cell induced by different concentrations of trichloroethylene. The 4th International Congress of Asian Society of Toxicology. Chinese Journal of Pharmacology and Toxicology, Zhuhai,China, Poster 2006, Jun, 20(3):258(P3-23).
人才培養(yǎng):
2006年至2020年,共指導(dǎo)碩士研究生30名、博士研究生5名、博士后5名。